Antimicrobial resistance: the example of Staphylococcus aureus
FD Lowy - The Journal of clinical investigation, 2003 - Am Soc Clin Investig
S. aureus infections in intensive care units in the National Nosocomial Infections
Surveillance System. Data include the total number of infections from 1987 to 1997. Isolates …
Surveillance System. Data include the total number of infections from 1987 to 1997. Isolates …
Immune evasion by staphylococci
TJ Foster - Nature reviews microbiology, 2005 - nature.com
Staphylococcus aureus can cause superficial skin infections and, occasionally, deep-seated
infections that entail spread through the blood stream. The organism expresses several …
infections that entail spread through the blood stream. The organism expresses several …
Insights on Evolution of Virulence and Resistance from the Complete Genome Analysis of an Early Methicillin-Resistant Staphylococcus aureus Strain and a Biofilm-Producing …
Staphylococcus aureus is an opportunistic pathogen and the major causative agent of
numerous hospital-and community-acquired infections. Staphylococcus epidermidis has …
numerous hospital-and community-acquired infections. Staphylococcus epidermidis has …
Molecular Mechanisms of Staphylococcus aureus Iron Acquisition
The unique redox potential of iron makes it an ideal cofactor in diverse biochemical
reactions. Iron is therefore vital for the growth and proliferation of nearly all organisms …
reactions. Iron is therefore vital for the growth and proliferation of nearly all organisms …
The enigma of sepsis
NC Riedemann, RF Guo… - The Journal of clinical …, 2003 - Am Soc Clin Investig
Sepsis remains a serious cause of morbidity and mortality, and the pathophysiology of the
disease is not clear. The definition of the clinical manifestations of sepsis is ever evolving …
disease is not clear. The definition of the clinical manifestations of sepsis is ever evolving …
Staphylococcus colonization of the skin and antimicrobial peptides
M Otto - Expert review of dermatology, 2010 - Taylor & Francis
Staphylococci are the most abundant skin-colonizing bacteria and the most important
causes of nosocomial infections and community-associated skin infections. Molecular …
causes of nosocomial infections and community-associated skin infections. Molecular …
From empiricism to rational design: a personal perspective of the evolution of vaccine development
E De Gregorio, R Rappuoli - Nature Reviews Immunology, 2014 - nature.com
Vaccination, which is the most effective medical intervention that has ever been introduced,
originated from the observation that individuals who survived a plague or smallpox would …
originated from the observation that individuals who survived a plague or smallpox would …
Current concepts on the virulence mechanisms of meticillin-resistant Staphylococcus aureus
RR Watkins, MZ David… - Journal of medical …, 2012 - microbiologyresearch.org
Meticillin-resistant Staphylococcus aureus (MRSA) strains are prevalent bacterial pathogens
that cause both health care and community-associated infections. Increasing resistance to …
that cause both health care and community-associated infections. Increasing resistance to …
Fighting bacterial infections—future treatment options
J Fernebro - Drug Resistance Updates, 2011 - Elsevier
This review summarizes ongoing research aimed at finding novel drugs as alternatives to
traditional antibiotics. Anti-virulence approaches, phage therapy and therapeutic antibodies …
traditional antibiotics. Anti-virulence approaches, phage therapy and therapeutic antibodies …
Discovery of a novel class of highly conserved vaccine antigens using genomic scale antigenic fingerprinting of pneumococcus with human antibodies
C Giefing, AL Meinke, M Hanner, T Henics… - The Journal of …, 2008 - rupress.org
Pneumococcus is one of the most important human pathogens that causes life-threatening
invasive diseases, especially at the extremities of age. Capsular polysaccharides (CPSs) …
invasive diseases, especially at the extremities of age. Capsular polysaccharides (CPSs) …