Conduct disorder

G Fairchild, DJ Hawes, PJ Frick… - Nature Reviews …, 2019 - nature.com
Conduct disorder (CD) is a common and highly impairing psychiatric disorder that usually
emerges in childhood or adolescence and is characterized by severe antisocial and …

Reduced microbiome alpha diversity in young patients with ADHD

A Prehn-Kristensen, A Zimmermann, L Tittmann… - PloS one, 2018 - journals.plos.org
ADHD is a psychiatric disorder which is characterized by hyperactivity, impulsivity and
attention problems. Due to recent findings of microbial involvement in other psychiatric …

Genomics of human aggression: current state of genome-wide studies and an automated systematic review tool

VV Odintsova, PJ Roetman, HF Ip, R Pool… - Psychiatric …, 2019 - journals.lww.com
There are substantial differences, or variation, between humans in aggression, with its
molecular genetic basis mostly unknown. This review summarizes knowledge on the genetic …

An integrated analysis of genes and functional pathways for aggression in human and rodent models

Y Zhang-James, N Fernàndez-Castillo, JL Hess… - Molecular …, 2019 - nature.com
Human genome-wide association studies (GWAS), transcriptome analyses of animal
models, and candidate gene studies have advanced our understanding of the genetic …

Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder

D Demontis, RK Walters, VM Rajagopal… - Nature …, 2021 - nature.com
Abstract Attention-Deficit/Hyperactivity Disorder (ADHD) is a childhood psychiatric disorder
often comorbid with disruptive behavior disorders (DBDs). Here, we report a GWAS meta …

Neural glycosylphosphatidylinositol-anchored proteins in synaptic specification

JW Um, J Ko - Trends in cell biology, 2017 - cell.com
Glycosylphosphatidylinositol (GPI)-anchored proteins are a specialized class of lipid-
associated neuronal membrane proteins that perform diverse functions in the dynamic …

Selenoprotein T: an essential oxidoreductase serving as a guardian of endoplasmic reticulum homeostasis

H Pothion, C Jehan, H Tostivint, D Cartier… - Antioxidants & redox …, 2020 - liebertpub.com
Significance: Selenoproteins incorporate the essential nutrient selenium into their
polypeptide chain. Seven members of this family reside in the endoplasmic reticulum (ER) …

The Role of selenoproteins SELENOM and SELENOT in the regulation of apoptosis, ER stress, and calcium homeostasis in the A-172 human glioblastoma cell line

EG Varlamova, MV Goltyaev, EA Turovsky - Biology, 2022 - mdpi.com
Simple Summary In this work, we present for the first time the effects of the suppression of
the activity of poorly studied selenoproteins SELENOM and SELENOT in human …

A proteomic screen of neuronal cell-surface molecules reveals IgLONs as structurally conserved interaction modules at the synapse

FM Ranaivoson, LS Turk, S Ozgul, S Kakehi… - Structure, 2019 - cell.com
In the developing brain, cell-surface proteins play crucial roles, but their protein-protein
interaction network remains largely unknown. A proteomic screen identified 200 interactions …

The role of IgLON cell adhesion molecules in neurodegenerative diseases

M Salluzzo, C Vianello, S Abdullatef, R Rimondini… - Genes, 2023 - mdpi.com
In the brain, cell adhesion molecules (CAMs) are critical for neurite outgrowth, axonal
fasciculation, neuronal survival and migration, and synapse formation and maintenance …