Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) provide a
human-relevant platform for cardiac function assessment. Alternative assays using hiPSC …

Salivary gland (SG) dysfunction, due to radiotherapy, disease, or aging, is a clinical
manifestation that has the potential to cause severe oral and/or systemic diseases and …

Human pluripotent stem cells (hPSCs), derived from individuals or genetically modified with
disease-related mutations and variants, have revolutionised studies of human disease …

Human pluripotent stem cell derived cardiomyocytes (hPSC-CMs) represent an
inexhaustible cell source for in vitro disease modeling, drug discovery and toxicity …

The maturation of human stem cell-derived cardiomyocytes (hSC-CMs) has been a major
challenge to further expand the scope of their application. Over the past years, several …

Brugada syndrome (BrS) is an inherited and rare cardiac arrhythmogenic disease
associated with an increased risk of ventricular fibrillation and sudden cardiac death …

The involvement of cell-derived extracellular matrix (CDM) in assembling tissue engineering
scaffolds has yielded significant results. CDM possesses excellent characteristics, such as …

Previously, we showed that extracellular matrices (ECMs), produced ex vivo by various
types of stromal cells, direct bone marrow mesenchymal stem cells (BM-MSCs) in a tissue …

Recent breakthroughs in developing human-relevant organotypic models led to the building
of highly resemblant tissue constructs that hold immense potential for transplantation, drug …

Cardiovascular disease (CVD) caused by anti-cancer drug-induced cardiotoxicity is now the
second leading cause of mortality among cancer survivors. It is necessary to establish …