Mucins: the frontline defence of the lung
C Ridley, DJ Thornton - Biochemical Society Transactions, 2018 - portlandpress.com
Mucus plays a vital role in protecting the lungs from environmental factors, but conversely, in
muco-obstructive airway disease, mucus becomes pathologic. In its protective role, mucus …
muco-obstructive airway disease, mucus becomes pathologic. In its protective role, mucus …
Mucin-bacterial interactions in the human oral cavity and digestive tract
M Derrien, MWJ van Passel… - Gut …, 2010 - Taylor & Francis
Mucins are a family of heavily glycosylated proteins that are the major organic components
of the mucus layer, the protective layer covering the epithelial cells in many human and …
of the mucus layer, the protective layer covering the epithelial cells in many human and …
# COVIDisAirborne: AI-enabled multiscale computational microscopy of delta SARS-CoV-2 in a respiratory aerosol
A Dommer, L Casalino, F Kearns… - … journal of high …, 2023 - journals.sagepub.com
We seek to completely revise current models of airborne transmission of respiratory viruses
by providing never-before-seen atomic-level views of the SARS-CoV-2 virus within a …
by providing never-before-seen atomic-level views of the SARS-CoV-2 virus within a …
Structural analysis of N-and O-glycans released from glycoproteins
This protocol shows how to obtain a detailed glycan compositional and structural profile from
purified glycoproteins or protein mixtures, and it can be used to distinguish different isobaric …
purified glycoproteins or protein mixtures, and it can be used to distinguish different isobaric …
Human body fluid proteome analysis
The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …
The interaction of the gut microbiota with the mucus barrier in health and disease in human
AP Corfield - Microorganisms, 2018 - mdpi.com
Glycoproteins are major players in the mucus protective barrier in the gastrointestinal and
other mucosal surfaces. In particular the mucus glycoproteins, or mucins, are responsible for …
other mucosal surfaces. In particular the mucus glycoproteins, or mucins, are responsible for …
Mucin‐type O‐glycosylation–putting the pieces together
PH Jensen, D Kolarich, NH Packer - The FEBS journal, 2010 - Wiley Online Library
The O‐glycosylation of Ser and Thr by N‐acetylgalactosamine‐linked (mucin‐type)
oligosaccharides is often overlooked in protein analysis. Three characteristics make O …
oligosaccharides is often overlooked in protein analysis. Three characteristics make O …
A complex, but uniform O-glycosylation of the human MUC2 mucin from colonic biopsies analyzed by nanoLC/MSn
JM Holmén Larsson, H Karlsson, H Sjövall… - …, 2009 - academic.oup.com
High-sensitivity glycan profiling providing detailed structural information is very important in
the search for glycan disease markers. By combining a straight-forward and fast preparation …
the search for glycan disease markers. By combining a straight-forward and fast preparation …
Mucin O-glycans suppress quorum-sensing pathways and genetic transformation in Streptococcus mutans
Mucus barriers accommodate trillions of microorganisms throughout the human body while
preventing pathogenic colonization. In the oral cavity, saliva containing the mucins MUC5B …
preventing pathogenic colonization. In the oral cavity, saliva containing the mucins MUC5B …
Saliva proteome research: current status and future outlook
BL Schulz, J Cooper-White… - Critical reviews in …, 2013 - Taylor & Francis
Human saliva harbours proteins of clinical relevance and about 30% of blood proteins are
also present in saliva. This highlights that saliva can be used for clinical applications just as …
also present in saliva. This highlights that saliva can be used for clinical applications just as …