[HTML][HTML] Kisspeptins and the neuroendocrine control of reproduction: Recent progress and new frontiers in kisspeptin research
V Sobrino, MS Avendano, C Perdices-Lopez… - Frontiers in …, 2022 - Elsevier
In late 2003, a major breakthrough in our understanding of the mechanisms that govern
reproduction occurred with the identification of the reproductive roles of kisspeptins …
reproduction occurred with the identification of the reproductive roles of kisspeptins …
[HTML][HTML] Carbamate pesticides: shedding light on their impact on the male reproductive system
Carbamates are widely used and known around the world as pesticides in spite of also
having medical applications. This class of chemicals is classified as acetylcholinesterase …
having medical applications. This class of chemicals is classified as acetylcholinesterase …
[HTML][HTML] Sexual dimorphism in kisspeptin signaling
EB Lee, I Dilower, CA Marsh, MW Wolfe, S Masumi… - Cells, 2022 - mdpi.com
Kisspeptin (KP) and kisspeptin receptor (KPR) are essential for the onset of puberty,
development of gonads, and maintenance of gonadal function in both males and females …
development of gonads, and maintenance of gonadal function in both males and females …
Hierarchical deployment of Tbx3 dictates the identity of hypothalamic KNDy neurons to control puberty onset
X Shi, Y Zhuang, Z Chen, M Xu, J Kuang, XL Sun… - Science …, 2022 - science.org
The neuroendocrine system consists of a heterogeneous collection of neuropeptidergic
neurons in the brain, among which hypothalamic KNDy neurons represent an indispensable …
neurons in the brain, among which hypothalamic KNDy neurons represent an indispensable …
Hypothalamic overexpression of makorin ring finger protein 3 results in delayed puberty in female mice
SA Roberts, L Naulé, S Chouman, T Johnson… - …, 2022 - academic.oup.com
Makorin ring finger protein 3 (MKRN3) is an important neuroendocrine player in the control
of pubertal timing and upstream inhibitor of gonadotropin-releasing hormone secretion. In …
of pubertal timing and upstream inhibitor of gonadotropin-releasing hormone secretion. In …
[HTML][HTML] Transcriptional profiling of Kiss1 neurons from arcuate and rostral periventricular hypothalamic regions in female mice
S Manchishi, M Prater, WH Colledge - Reproduction, 2024 - rep.bioscientifica.com
In brief The transcriptional profiles of Kiss1 neurons from the arcuate and the rostral
periventricular region of the third ventricle of the hypothalamus have been directly compared …
periventricular region of the third ventricle of the hypothalamus have been directly compared …
Inactivating NHLH2 variants cause idiopathic hypogonadotropic hypogonadism and obesity in humans
AK Topaloglu, E Simsek, MA Kocher, J Mammadova… - Human genetics, 2022 - Springer
Metabolism has a role in determining the time of pubertal development and fertility.
Nonetheless, molecular/cellular pathways linking metabolism/body weight to …
Nonetheless, molecular/cellular pathways linking metabolism/body weight to …
Agouti‐related peptide neuronal silencing overcomes delayed puberty in neonatally underfed male mice
C Decourt, GADP Connolly, C Ancel… - Journal of …, 2022 - Wiley Online Library
Agouti‐related peptide (AgRP) neurons are thought to indirectly regulate the activity of
hypothalamic gonadotrophin‐releasing hormone neurons which control fertility. AgRP …
hypothalamic gonadotrophin‐releasing hormone neurons which control fertility. AgRP …
[HTML][HTML] DNA Methylation in INA, NHLH2, and THBS4 Is Associated with Metastatic Disease in Renal Cell Carcinoma
O Katzendorn, I Peters, N Dubrowinskaja, JM Moog… - Cancers, 2021 - mdpi.com
Simple Summary Early prediction of aggressive cancer using biomarkers is thought to be
important for future improvements in the personalized treatment of renal cell carcinoma …
important for future improvements in the personalized treatment of renal cell carcinoma …
[HTML][HTML] In Silico Examination of Single Nucleotide Missense Mutations in NHLH2, a Gene Linked to Infertility and Obesity
AT Madsen, DJ Good - International Journal of Molecular Sciences, 2023 - mdpi.com
Continual advances in our understanding of the human genome have led to exponential
increases in known single nucleotide variants. The characterization of each of the variants …
increases in known single nucleotide variants. The characterization of each of the variants …