[HTML][HTML] The roles of glutathione and oxidative stress in diabetes and COVID-19

E Los, G Ford, D Tuell, D Macariola Jr, W Stone - Oxygen, 2024 - mdpi.com
Evidence suggests that COVID-19 infection increases the risk of type 1 (T1D) and type 2
diabetes (T2D). Diabetes, in turn, increases COVID-19 susceptibility and contributes to …

Glutathione Induces Keap1 S-Glutathionylation and Mitigates Oscillating Glucose-Induced β-Cell Dysfunction by Activating Nrf2

X Chen, Q Zhou, H Chen, J Bai, R An, K Zhang… - Antioxidants, 2024 - mdpi.com
Glutathione (GSH), a robust endogenous antioxidant, actively participates in the modulation
of the redox status of cysteine residues in proteins. Previous studies have indicated that …

Astaxanthin improves lipotoxicity, lipid peroxidation and oxidative stress in kidney of sucrose-rich diet-fed rats

MBV Joubert, PI Ingaramo, P Collins… - The Journal of …, 2025 - Elsevier
Metabolic Syndrome (MS) is a cluster of metabolic risk factors, characterized by abdominal
obesity, dyslipidemia, hypertension, insulin resistance, among others. The purpose of the …

Glutathione and a Pool of Metabolites Partly Related to Oxidative Stress Are Associated with Low and High Myopia in an Altered Bioenergetic Environment

S Mérida, A Návea, C Desco, B Celda… - Antioxidants, 2024 - mdpi.com
Oxidative stress forms part of the molecular basis contributing to the development and
manifestation of myopia, a refractive error with associated pathology that is increasingly …

Tauroursodeoxycholic Acid (TUDCA) Relieves Streptozotocin (STZ)-Induced Diabetic Rat Model via Modulation of Lipotoxicity, Oxidative Stress, Inflammation, and …

NA Mohamed, MT Ithmil, AI Elkady… - International Journal of …, 2024 - mdpi.com
Tauroursodeoxycholic acid (TUDCA) is approved for the treatment of liver diseases.
However, the antihyperglycemic effects/mechanisms of TUDCA are still less clear. The …

The link between the ANPEP gene and type 2 diabetes mellitus may be mediated by the disruption of glutathione metabolism and redox homeostasis

Y Korvyakova, I Azarova, E Klyosova, M Postnikova… - Gene, 2025 - Elsevier
Aminopeptidase N (ANPEP), a membrane-associated ectoenzyme, has been identified as a
susceptibility gene for type 2 diabetes (T2D) by genome-wide association and transcriptome …

Glutathione, Glutathione S Transferase Levels and M1/T1 Null Genotype Association with Covid-19 Infection Combined with Diabetes Mellitus Type 2 Patients

AM Amshawee, R Abboud, I Al-Mamorri, M Ahmed… - TWIST, 2024 - twistjournal.net
Background: The companied of covid-19 infection with other disease has been reported to
be more influences in infection progressing and development, this regarding the …

Prospective study on Glutathione expression and immune response in the oral cavity of diabetic patients

DA Slăvescu, O Frățilă, AE Moca… - Medicine in …, 2024 - medicineinevolution.ro
Aim and objectives: This study aimed to investigate the association between antioxidant
protection factors (glutathione and MTH1/MUTH) and immune response (CD3-lymphocyte T …