DNA methylation as a mediator of associations between the environment and chronic diseases: A scoping review on application of mediation analysis
ABSTRACT DNA methylation (DNAm) is one of the most studied epigenetic modifications.
DNAm has emerged as a key biological mechanism and biomarkers to test associations …
DNAm has emerged as a key biological mechanism and biomarkers to test associations …
Comparison of different cell type correction methods for genome-scale epigenetics studies
Background Whole blood is frequently utilized in genome-wide association studies of DNA
methylation patterns in relation to environmental exposures or clinical outcomes. These …
methylation patterns in relation to environmental exposures or clinical outcomes. These …
Assessment of DNA methylation patterns in the bone and cartilage of a nonhuman primate model of osteoarthritis
G Housman, LM Havill, EE Quillen, AG Comuzzie… - Cartilage, 2019 - journals.sagepub.com
Objective Osteoarthritis (OA) affects humans and several other animals. Thus, the
mechanisms underlying this disorder, such as specific skeletal tissue DNA methylation …
mechanisms underlying this disorder, such as specific skeletal tissue DNA methylation …
Bioinformatic and biostatistic methods for DNA methylome analysis of obesity
SAC Voisin - Computational Epigenetics and Diseases, 2019 - Elsevier
The implication of DNA methylation in the pathogenesis of obesity is increasingly
recognized as candidate gene and epigenome-wide association studies have shown DNA …
recognized as candidate gene and epigenome-wide association studies have shown DNA …
Bioinformatic and biostatistic analysis of epigenetic data from humans and mice in the context of obesity and its complications
S Voisin - 2016 - diva-portal.org
Worldwide obesity has more than doubled since 1980 and at least 2.8 million people die
each year as a result of being overweight or obese. An elevated body weight is the result of …
each year as a result of being overweight or obese. An elevated body weight is the result of …
[图书][B] Primate Skeletal Epigenetics: Evolutionary Implications of DNA Methylation Patterns in the Skeletal Tissues of Human and Nonhuman Primates
G Housman - 2017 - search.proquest.com
Within the primate lineage, skeletal traits that contribute to inter-specific anatomical variation
and enable varied niche occupations and forms of locomotion are often described as the …
and enable varied niche occupations and forms of locomotion are often described as the …