The implication of vitamin D and autoimmunity: a comprehensive review

CY Yang, PSC Leung, IE Adamopoulos… - Clinical reviews in …, 2013 - Springer
Historically, vitamin D has been associated with the regulation of bone metabolism.
However, increasing evidence demonstrates a strong association between vitamin D …

[PDF][PDF] Vitamin D and autoimmune diseases: is vitamin D receptor (VDR) polymorphism the culprit

G Bizzaro, A Antico, A Fortunato, N Bizzaro - Isr Med Assoc J, 2017 - ima.org.il
IMAJ• VOL 19• JULY 2017 ulation of cellular growth, proliferation, apoptosis, and immune
cell activation [2]. Awareness of a the role vitamin D takes in the regulation of immune …

The role of vitamin d deficiency in the incidence, progression, and complications of type 1 diabetes mellitus

M Chakhtoura, ST Azar - International journal of endocrinology, 2013 - Wiley Online Library
The “nonclassic” role of 1, 25‐dihydroxyvitamin D3 (1, 25 (OH) 2D3) has been recently
widely recognized. In type 1 diabetes mellitus (T1D), it plays an immunomodulatory role …

Polymorphisms in the vitamin D receptor gene and type 1 diabetes mellitus risk: an update by meta-analysis

J Zhang, W Li, J Liu, W Wu, H Ouyang, Q Zhang… - Molecular and cellular …, 2012 - Elsevier
Four well known polymorphisms (BsmI, FokI, ApaI, TaqI) in the VDR gene have been
implicated in susceptibility to type 1 diabetes mellitus (T1DM), but the results to date have …

Vitamin D status and vitamin D receptor gene polymorphisms and susceptibility to type 1 diabetes in Egyptian children

SH Abd-Allah, HF Pasha, HA Hagrass, AA Alghobashy - Gene, 2014 - Elsevier
Background Type 1 diabetes mellitus (T1DM) is recognized as a T-cell-mediated
autoimmune disease. Vitamin D compounds are known to suppress T-cell activation by …

Quantitative assessment of the associations between four polymorphisms (FokI, ApaI, BsmI, TaqI) of vitamin D receptor gene and risk of diabetes mellitus

Q Wang, B Xi, KH Reilly, M Liu, M Fu - Molecular biology reports, 2012 - Springer
The vitamin D receptor (VDR) gene polymorphisms have been suggested to be involved in
the development of diabetes mellitus, including type 1 diabetes (T1DM) and type 2 diabetes …

Vitamin D in ankylosing spondylitis: review and meta-analysis

G Cai, L Wang, D Fan, L Xin, L Liu, Y Hu, N Ding… - Clinica chimica acta, 2015 - Elsevier
Background The role of vitamin D in ankylosing spondylitis (AS) is largely unknown. This
paper aims to examine the association between serum vitamin D levels and susceptibility …

Association between genetic variants and diabetes mellitus in Iranian populations: a systematic review of observational studies

M Khodaeian, S Enayati… - Journal of diabetes …, 2015 - Wiley Online Library
Introduction. Diabetes mellitus as the most prevalent metabolic disease is a multifactorial
disease which is influenced by environmental and genetic factors. In this systematic review …

Single-nucleotide polymorphisms as important risk factors of diabetes among Middle East population

I Akhlaghipour, AR Bina, MR Mogharrabi, A Fanoodi… - Human Genomics, 2022 - Springer
Diabetes is a chronic metabolic disorder that leads to the dysfunction of various tissues and
organs, including eyes, kidneys, and cardiovascular system. According to the World Health …

Vitamin D receptor rs7975232, rs731236 and rs1544410 single nucleotide polymorphisms, and 25-hydroxyvitamin D levels in Egyptian children with type 1 diabetes …

AEA Ahmed, HM Sakhr, MH Hassan… - … syndrome and obesity …, 2019 - Taylor & Francis
Purpose: We aimed to examine the possible association role of vitamin D and vitamin D
receptor (VDR) single nucleotide polymorphisms (SNPs) in type 1 diabetes mellitus (T1DM) …