Cholangiocarcinoma (CCA) is a highly lethal adenocarcinoma of the hepatobiliary system,
which can be classified as intrahepatic, perihilar and distal. Each anatomic subtype has …

Metabolic reprogramming is a hallmark of cancer and allows tumour cells to meet the
increased energy demands required for rapid proliferation, invasion, and metastasis …

Malignant tumors are often multifactorial. Epidemiological studies have shown that
hyperglycemia raises the prevalence and mortality of certain malignancies, like breast, liver …

The association of cancer and diabetes mellitus (DM) has been studied for decades.
Hyperglycemia and the imbalance of hormones are factors that contribute to the molecular …

Hyperglycemia is a common feature of diabetes mellitus, considered as a risk factor for
cancer. However, its direct effects in cancer cell behavior are relatively unexplored. Herein …

Background: In a subset of severe asthma patients, chronic airway inflammation is
associated with infiltration of neutrophils, Th-17 cells and elevated expression of Th-17 …

Diabetes and cancer are worldwide chronic diseases with a major impact on the quality and
expectancy of life. Metabolic abnormalities observed during the onset and progression of …

Increased glucose utilization is a feature of cancer cells to support cell survival, proliferation,
and metastasis. An association between diabetes mellitus and cancer progression was …

Chronic hyperglycemia has been associated with an increased prevalence of pathological
conditions including cardiovascular disease, cancer, or various disorders of the immune …

Background/Aim: Cholangiocarcinoma (CCA) is an aggressive cancer for which standard
treatments are still ineffective. This study demonstrated the antiproliferative and anti …