Genetics and the placebo effect: the placebome
Placebos are indispensable controls in randomized clinical trials (RCTs), and placebo
responses significantly contribute to routine clinical outcomes. Recent neurophysiological …
responses significantly contribute to routine clinical outcomes. Recent neurophysiological …
[HTML][HTML] Hedonic and incentive signals for body weight control
E Egecioglu, KP Skibicka, C Hansson… - Reviews in Endocrine …, 2011 - Springer
Here we review the emerging neurobiological understanding of the role of the brain's reward
system in the regulation of body weight in health and in disease. Common obesity is …
system in the regulation of body weight in health and in disease. Common obesity is …
Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1
Recent studies have established the involvement of the fat mass and obesity-associated
gene (FTO) in metabolic disorders such as obesity and diabetes. However, the precise …
gene (FTO) in metabolic disorders such as obesity and diabetes. However, the precise …
Effects of tea and coffee on cardiovascular disease risk
Tea and coffee have been associated with risk of cardiovascular disease (CVD), both
positively and negatively. Epidemiological data suggest that black and green tea may …
positively and negatively. Epidemiological data suggest that black and green tea may …
Dopamine D1 receptor gene expression decreases in the nucleus accumbens upon long-term exposure to palatable food and differs depending on diet-induced …
J Alsiö, PK Olszewski, AH Norbäck, ZEA Gunnarsson… - Neuroscience, 2010 - Elsevier
The nucleus accumbens (NAcc) mediates feeding reward; its activity reflects tastants'
hedonic value. NAcc dopamine guides immediate responses to reward, however, its …
hedonic value. NAcc dopamine guides immediate responses to reward, however, its …
[HTML][HTML] Cancer biology and prevention in diabetes
SP Srivastava, JE Goodwin - Cells, 2020 - mdpi.com
The available evidence suggests a complex relationship between diabetes and cancer.
Epidemiological data suggest a positive correlation, however, in certain types of cancer, a …
Epidemiological data suggest a positive correlation, however, in certain types of cancer, a …
[HTML][HTML] Prenatal androgen exposure causes a sexually dimorphic transgenerational increase in offspring susceptibility to anxiety disorders
If and how obesity and elevated androgens in women with polycystic ovary syndrome
(PCOS) affect their offspring's psychiatric health is unclear. Using data from Swedish …
(PCOS) affect their offspring's psychiatric health is unclear. Using data from Swedish …
Catecholamines and obesity: effects of exercise and training
H Zouhal, S Lemoine-Morel, ME Mathieu, GA Casazza… - Sports Medicine, 2013 - Springer
Excess body fat in obese individuals can affect the catecholamine response to various
stimuli. Indeed, several studies report lower plasma catecholamine concentrations in obese …
stimuli. Indeed, several studies report lower plasma catecholamine concentrations in obese …
The role of obesity in the pathogenesis of hypertension
YE Bogaert, S Linas - Nature clinical practice Nephrology, 2009 - nature.com
The rapid rise in the incidence and prevalence of obesity and the concomitant increase in
the incidence and prevalence of hypertension have fueled investigation into the role of …
the incidence and prevalence of hypertension have fueled investigation into the role of …
Catechol-O-Methyltransferase (COMT): An Update on Its Role in Cancer, Neurological and Cardiovascular Diseases
Abstract Catechol-O-methyltransferase (COMT) is an enzyme that catalyses the methylation
of catechol substrates, classically in catecholamine metabolism, but also acting upon other …
of catechol substrates, classically in catecholamine metabolism, but also acting upon other …