[HTML][HTML] Cardiovascular Disease in Saudi Arabia: Facts and the way forward

AA Tash, RF Al-Bawardy - Journal of the Saudi Heart Association, 2023 - ncbi.nlm.nih.gov
Cardiovascular diseases (CVDs) remain a major health concern globally. While some risk
factors for CVDs are non-modifiable, other determinants like obesity, hypertension, type-2 …

New trends and therapies for familial hypercholesterolemia

F Alnouri, RD Santos - Journal of Clinical Medicine, 2022 - mdpi.com
Familial hypercholesterolemia (FH) is associated with an elevated risk of atherosclerosis.
The finding of monogenic defects indicates higher atherosclerotic risk in comparison with …

Familial hypercholesterolemia (FH) registry worldwide: A systematic review

A Amerizadeh, SH Javanmard, N Sarrafzadegan… - Current Problems in …, 2022 - Elsevier
Familial hypercholesterolemia (FH) is the most common genetic disease which accelerates
the development of premature coronary artery disease (CAD) in young adults if remains …

[HTML][HTML] Identifying significant genes and functionally enriched pathways in familial hypercholesterolemia using integrated gene co-expression network analysis

Z Awan, N Alrayes, Z Khan, M Almansouri… - Saudi Journal of …, 2022 - Elsevier
Familial hypercholesterolemia (FH) is a monogenic lipid disorder which promotes
atherosclerosis and cardiovascular diseases. Owing to the lack of sufficient published …

Clinical features of familial hypercholesterolemia in children and adults in EAS-FHSC Regional Center for rare diseases in Poland

J Lewek, A Konopka, E Starostecka… - Journal of Clinical …, 2021 - mdpi.com
Background: Familial hypercholesterolemia (FH) is a genetic autosomal co-dominant
metabolic disorder leading to elevated circulating concentrations of low-density lipoprotein …

Familial hypercholesterolaemia and coronary risk factors among patients with angiogram-proven premature coronary artery disease in an Asian cohort

SA Nazli, YA Chua, NA Mohd Kasim, Z Ismail… - Plos one, 2022 - journals.plos.org
Background Familial hypercholesterolaemia (FH) patients have elevated levels of low-
density lipoprotein cholesterol, rendering them at high risk of premature coronary artery …

Is liver transplant curative in homozygous familial hypercholesterolemia? A review of nine global cases

M Al Dubayee, M Kayikcioglu, JR van Lennep… - Advances in …, 2022 - Springer
Abstract Introduction Homozygous familial hypercholesterolemia (HoFH) is a rare, life-
threatening, inherited condition characterized by extremely elevated levels of low-density …

Multizonal observational study conducted by clinical practitioners on evolocumab use in subjects with hyperlipidemia in Saudi Arabia and Kuwait: Results from the …

K Al Faraidy, M Akbar, M Shehri, M Aljarallah… - PLoS …, 2023 - journals.plos.org
Objectives Dyslipidemia is a prevalent condition with significant morbidity and mortality
across the world, including in the Arabian Gulf. The present study aimed to describe the …

Management and clinical outcomes of patients with homozygous familial hypercholesteremia in Saudi Arabia

N Kholaif, TI Mohamed, IS Alharbi… - … Archives for Chest …, 2023 - monaldi-archives.org
We report the incidence, patient characteristic with clinical outcomes in patients with
homozygous familial hypercholesterolemia (HoFH) in Saudi Arabia. This is a retrospective …

Comorbidities with Familial Hypercholesterolemia (FH): A Systematic Review

G Vaseghi, SH Javanmard… - Current Problems in …, 2023 - Elsevier
Familial hypercholesterolemia (FH) is linked to high levels of low-density lipoprotein
cholesterol (LDL-C), atherosclerotic, and aortic stenosis to a lesser extent. We looked at the …