Challenges in the treatment of chronic wounds

RG Frykberg, J Banks - Advances in wound care, 2015 - liebertpub.com
Significance: Chronic wounds include, but are not limited, to diabetic foot ulcers, venous leg
ulcers, and pressure ulcers. They are a challenge to wound care professionals and …

Peripheral nerve regeneration: experimental strategies and future perspectives

A Faroni, SA Mobasseri, PJ Kingham… - Advanced drug delivery …, 2015 - Elsevier
Peripheral nerve injuries represent a substantial clinical problem with insufficient or
unsatisfactory treatment options. This review summarises all the events occurring after nerve …

Advancing frontiers in bone bioprinting

N Ashammakhi, A Hasan, O Kaarela… - Advanced …, 2019 - Wiley Online Library
Abstract Three‐dimensional (3D) bioprinting of cell‐laden biomaterials is used to fabricate
constructs that can mimic the structure of native tissues. The main techniques used for 3D …

Mesenchymal stem cells as therapeutics

B Parekkadan, JM Milwid - Annual review of biomedical …, 2010 - annualreviews.org
Mesenchymal stem cells (MSCs) are multipotent cells that are being clinically explored as a
new therapeutic for treating a variety of immune-mediated diseases. First heralded as a …

Advances of stem cell therapeutics in cutaneous wound healing and regeneration

S Kanji, H Das - Mediators of inflammation, 2017 - Wiley Online Library
Cutaneous wound healing is a complex multiple phase process, which overlaps each other,
where several growth factors, cytokines, chemokines, and various cells interact in a well …

Highlights on advancing frontiers in tissue engineering

N Ashammakhi, A GhavamiNejad, R Tutar… - … Engineering Part B …, 2022 - liebertpub.com
The field of tissue engineering continues to advance, sometimes in exponential leaps
forward, but also sometimes at a rate that does not fulfill the promise that the field imagined a …

The role of tissue engineering in articular cartilage repair and regeneration

L Zhang, J Hu, KA Athanasiou - Critical Reviews™ in …, 2009 - dl.begellhouse.com
Articular cartilage repair and regeneration continue to be largely intractable because of the
poor regenerative properties of this tissue. The field of articular cartilage tissue engineering …

A patch of detachable hybrid microneedle depot for localized delivery of mesenchymal stem cells in regeneration therapy

KJ Lee, Y Xue, J Lee, HJ Kim, Y Liu… - Advanced Functional …, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been widely used for regenerative therapy. In most
current clinical applications, MSCs are delivered by injection but face significant issues with …

Stem cell-delivery therapeutics for periodontal tissue regeneration

FM Chen, HH Sun, H Lu, Q Yu - Biomaterials, 2012 - Elsevier
Periodontitis, an inflammatory disease, is the most common cause of tooth loss in adults.
Attempts to regenerate the complex system of tooth-supporting apparatus (ie, the …

Homing of endogenous stem/progenitor cells for in situ tissue regeneration: promises, strategies, and translational perspectives

FM Chen, LA Wu, M Zhang, R Zhang, HH Sun - Biomaterials, 2011 - Elsevier
Stem cell-based therapy has been one of the best documented approaches in regenerative
medicine, promising cures for a multitude of diseases and disorders. However, the ex vivo …