Critical congenital heart disease (cCHD) has neurodevelopmental sequelae that can carry
into adulthood, which may be due to aberrant brain development or brain injury in the …

Adverse intrauterine events may profoundly impact fetal risk for future adult diseases. The
mechanisms underlying this increased vulnerability are complex and remain poorly …

Background Knowledge about extracardiac anomalies (ECA) in fetal congenital heart
disease (CHD) can improve our understanding of the developmental origins of various …

Following the improvements in the clinical management of patients with congenital heart
disease (CHD) and their increased survival, neurodevelopmental outcome has become an …

Background Fetal ventriculomegaly is the the most common intracranial abnormality
detected antenatally. When ventriculomegaly is mild and the only, isolated, abnormality …

Children born with congenital heart disease (CHD) have seen a dramatic decrease in
mortality thanks to surgical innovations. However, there are numerous risk factors …

Antenatal assessment of congenital heart disease and associated anomalies by ultrasound
has improved perinatal care. Fetal cardiovascular MRI and fetal brain MRI are rapidly …

Background Increasing evidence supports an association among congenital heart disease
(CHD), structural brain lesions on neuroimaging, and increased risk of neurodevelopmental …

Objective The purpose of this study is to establish a reference of intracranial structure
volumes in normal fetuses ranging from 19 to 37 weeks' gestation (mean 27 weeks) …

Background Several published studies have shown alterations of brain development in third‐
trimester fetuses with congenital heart disease (CHD). However, little is known about the …