To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …

Intercellular communication is a key feature of cancer progression and metastasis.
Extracellular vesicles (EVs) are generated by all cells, including cancer cells, and recent …

Exosomes are a subgroup of nanosized extracellular vesicles enclosed by a lipid bilayer
membrane and secreted by most eukaryotic cells. They represent a route of intercellular …

Exosomes are well-known key mediators of intercellular communication and contribute to
various physiological and pathological processes. Their biogenesis involves four key steps …

The field of extracellular vesicle (EV) research has developed rapidly over the last decade
from the study of fundamental biology to a subject of significant clinical relevance. The …

Background Despite advances in early detection and therapies, cancer is still one of the
most common causes of death worldwide. Since each tumor is unique, there is a need to …

Aging is a complex biological process accompanied by a progressive decline in the physical
function of the organism and an increased risk of age-related chronic diseases such as …

Extracellular vesicles (EVs) are gaining increasing attention for diagnostic and therapeutic
applications in various diseases. These natural nanoparticles benefit from favorable safety …

Cancer-derived extracellular vesicles (EVs) are regarded as having promising potential to
be used as therapeutics and disease biomarkers. Mechanistically, EVs have been shown to …

Cellular senescence is a physiological mechanism whereby a proliferating cell undergoes a
stable cell cycle arrest upon damage or stress and elicits a secretory phenotype. This highly …