[HTML][HTML] Oxidative Stress in Kidney Injury and Hypertension
WJ Arendshorst, AE Vendrov, N Kumar, SK Ganesh… - Antioxidants, 2024 - mdpi.com
Hypertension (HTN) is a major contributor to kidney damage, leading to conditions such as
nephrosclerosis and hypertensive nephropathy, significant causes of chronic kidney disease …
nephrosclerosis and hypertensive nephropathy, significant causes of chronic kidney disease …
Canagliflozin improves coronary microvascular vasodilation and increases absolute blood flow to the myocardium independent of angiogenesis
D Banerjee, SA Sabe, H Xing, C Xu, M Sabra… - The Journal of Thoracic …, 2023 - Elsevier
Objectives Sodium-glucose cotransporter-2 inhibitor, canagliflozin, improves myocardial
perfusion to ischemic territory without accompanying changes in vascular density. We aimed …
perfusion to ischemic territory without accompanying changes in vascular density. We aimed …
Crucial role for sensory nerves and Na/H exchanger inhibition in dapagliflozin-and empagliflozin-induced arterial relaxation
EA Forrester, M Benítez-Angeles… - Cardiovascular …, 2024 - academic.oup.com
Aims Sodium/glucose transporter 2 (SGLT2 or SLC5A2) inhibitors lower blood glucose and
are also approved treatments for heart failure independent of raised glucose. Various …
are also approved treatments for heart failure independent of raised glucose. Various …
Neflamapimod inhibits endothelial cell activation, adhesion molecule expression, leukocyte attachment and vascular inflammation by inhibiting p38 MAPKα and NF …
Neflamapimod, a selective inhibitor of the alpha isoform of p38 mitogen-activated protein
kinase (MAPKα), was investigated for its potential to inhibit lipopolysaccharide (LPS) …
kinase (MAPKα), was investigated for its potential to inhibit lipopolysaccharide (LPS) …
Blockade of Voltage‐Gated K+ Channels in Rabbit Coronary Arterial Smooth Muscle Cells by the Antipsychotic Drug Zotepine
W Zhuang, M Park, J Jeong, HR Kim… - Journal of Applied …, 2024 - Wiley Online Library
Zotepine is a second‐generation antipsychotic that demonstrates significant efficacy in
antagonizing D2 and 5‐HT2A receptors. Although clinical investigations have shown that …
antagonizing D2 and 5‐HT2A receptors. Although clinical investigations have shown that …
Empagliflozin Induces Vascular Relaxation in Rat Coronary Artery Due to Activation of BK Channels
Q Kong, L Qian, L Zhang, H Liu, F Yang… - Diabetes, Metabolic …, 2024 - Taylor & Francis
Purpose The aim of this study was to investigate the effects and mechanisms of SGLT2
inhibitor empagliflozin on diabetic coronary function. Methods A rat diabetic model was …
inhibitor empagliflozin on diabetic coronary function. Methods A rat diabetic model was …
Crucial role for Sodium Hydrogen Exchangers in SGLT2 inhibitor-induced arterial relaxations
EA Forrester, M Benítez-Angeles, KE Redford… - bioRxiv, 2023 - biorxiv.org
Introduction Sodium dependent glucose transporter 2 (SGLT2 or SLC5A2) inhibitors
effectively lower blood glucose and are also approved treatments for heart failure …
effectively lower blood glucose and are also approved treatments for heart failure …
Correlation and Successive Role of Synbiotics to Manage Blood Pressure
The effective management of hypertension, a prevalent cardiovascular condition, requires
innovative approaches. This chapter examines the emerging field of synbiotics and their …
innovative approaches. This chapter examines the emerging field of synbiotics and their …
Étude numérique des Dispositifs d'Assistance Ventriculaire pour l'optimisation de leur utilisation et la limitation des complications cliniques
L Marcel - 2023 - pastel.hal.science
L'insuffisance cardiaque est une maladie mortelle très répandue au sein du monde
moderne. Faute de donneurs, diverses thérapies à long-terme ont été mises en place pour …
moderne. Faute de donneurs, diverses thérapies à long-terme ont été mises en place pour …