Circuit-level theories for sensory dysfunction in autism: convergence across mouse models

HR Monday, HC Wang, DE Feldman - Frontiers in Neurology, 2023 - frontiersin.org
Individuals with autism spectrum disorder (ASD) exhibit a diverse range of behavioral
features and genetic backgrounds, but whether different genetic forms of autism involve …

[HTML][HTML] Parvalbumin-Positive Neurons in the Neocortex: A Review

R Druga, M Salaj, ALR Azzat - Physiological research, 2023 - ncbi.nlm.nih.gov
The calcium binding protein parvalbumin (PV) in the mammalian neocortex is expressed in
a subpopulation of cortical GABAergic inhibitory interneurons. PV–producing interneurons …

Hippocampal parvalbumin interneurons play a critical role in memory development

JM Miranda, E Cruz, B Bessières, CM Alberini - Cell reports, 2022 - cell.com
Episodic memories formed in early childhood rapidly decay, but their latent traces remain
stored long term. These memories require the dorsal hippocampus (dHPC) and seem to …

Experience-dependent plasticity of gustatory insular cortex circuits and taste preferences

HC Schiff, JF Kogan, M Isaac, LA Czarnecki… - Science …, 2023 - science.org
Early experience with food influences taste preference in adulthood. How gustatory
experience influences development of taste preferences and refinement of cortical circuits …

Social play behavior is critical for the development of prefrontal inhibitory synapses and cognitive flexibility in rats

A Bijlsma, A Omrani, M Spoelder… - Journal of …, 2022 - Soc Neuroscience
Sensory driven activity during early life is critical for setting up the proper connectivity of the
sensory cortices. We ask here whether social play behavior, a particular form of social …

Selective deletion of Methyl CpG binding protein 2 from parvalbumin interneurons in the auditory cortex delays the onset of maternal retrieval in mice

DD Rupert, AH Pagliaro, J Choe… - Journal of …, 2023 - Soc Neuroscience
Mutations in MECP2 cause the neurodevelopmental disorder Rett syndrome. MECP2 codes
for methyl CpG binding protein 2 (MECP2), a transcriptional regulator that activates genetic …

Children with autism spectrum disorder and abnormalities of clinical eeg: a qualitative review

C Bosetti, L Ferrini, AR Ferrari, E Bartolini… - Journal of Clinical …, 2024 - mdpi.com
Over the last decade, the comorbidity between Autism Spectrum Disorder (ASD) and
epilepsy has been widely demonstrated, and many hypotheses regarding the common …

Decreased extrasynaptic δ‐GABAA receptors in PNN‐associated parvalbumin interneurons correlates with anxiety in APP and tau mouse models of Alzheimer's …

W Zhang, T Liu, J Li, J Singh, A Chan… - British Journal of …, 2024 - Wiley Online Library
Background Alzheimer's disease (AD) is associated with gradual memory loss and anxiety
which affects~ 75% of AD patients. This study investigated whether AD‐associated anxiety …

Plasticity in auditory cortex during parenthood

B Haimson, A Mizrahi - Hearing Research, 2023 - Elsevier
Most animals display robust parental behaviors that support the survival and well-being of
their offspring. The manifestation of parental behaviors is accompanied by physiological and …

[HTML][HTML] Cell-type-specific representation of spatial context in the rat prefrontal cortex

H Brünner, H Kim, S Ährlund-Richter, JA van Lunteren… - Iscience, 2024 - cell.com
The ability to represent one's own position in relation to cues, goals, or threats is crucial to
successful goal-directed behavior. Using optotagging in knock-in rats expressing Cre …