Renal ischemia-reperfusion (IR) contributes to the development of ischemic acute renal
failure (ARF). Multi-factorial processes are involved in the development and progression of …

Introduction In multiple studies, involvement of oxidative stress in the pathogenesis of
methotrexate (MTX)-mediated liver damage has been confirmed. Use of many drugs has …

In this study, the antioxidant effect of aminoguanidine on nephrotoxicity of a single dose of
cisplatin is investigated and compared with the effects of well-known antioxidants vitamin C …

The effects of montelukast against methotrexate‐induced liver damage were investigated.
35 Wistar albino female rats were divided into 5 groups as follows: group I: control; group II …

OBJECTIVE: Hepatic fibrosis is a severe liver condition characterized by abnormal fibroblast
activity, excessive extracellular matrix deposition, inflammation, and structural alterations …

Oxidative stress produces macromolecules dysfunction and cellular damage. Renal
ischemia-reperfusion injury (IRI) induces oxidative stress, inflammation, epithelium and …

Purpose: This experimental study was designed to explore the protective effect of apocynin,
the NADPH-oxidase inhibitor, on kidney damage induced by ischemia/reperfusion (I/R) in a …

Abstract Background/Aims: This experimental study was designed to investigate protective
and therapeutic effects of Dexpanthenol (Dxp), an alcoholic analogue of pantothenic acid …

Background This study evaluated the effects of allopurinol (ALP), a xanthine oxidase
inhibitor, and apocynin (APC), a NADPH oxidase inhibitor, administered alone or together …

The purpose of the study was to explore the protective and therapeutic effects of
dexpanthenol (DEX) on isoproterenol (ISO)‐induced cardiac damage. Forty rats were …