Non‐provitamin A and provitamin A carotenoids as immunomodulators: Recommended dietary allowance, therapeutic index, or personalized nutrition?

E Toti, CYO Chen, M Palmery… - Oxidative medicine …, 2018 - Wiley Online Library
Vegetables and fruits contain non‐provitamin A (lycopene, lutein, and zeaxanthin) and
provitamin A (β‐carotene, β‐cryptoxanthin, and α‐carotene) carotenoids. Within these …

Medicinal prospects of antioxidants from algal sources in cancer therapy

UT Ferdous, ZNB Yusof - Frontiers in Pharmacology, 2021 - frontiersin.org
Though cancer therapeutics can successfully eradicate cancerous cells, the effectiveness of
these medications is mostly restricted to several deleterious side effects. Therefore, to …

Reduction of New Heterotopic Ossification (HO) in the Open‐Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP)

RJ Pignolo, EC Hsiao, M Al Mukaddam… - Journal of Bone and …, 2023 - academic.oup.com
Fibrodysplasia ossificans progressiva (FOP) is an ultra‐rare, severely disabling genetic
disorder of progressive heterotopic ossification (HO). The single‐arm, open‐label, phase 3 …

Soy, red clover, and isoflavones and breast cancer: a systematic review

H Fritz, D Seely, G Flower, B Skidmore, R Fernandes… - PloS one, 2013 - journals.plos.org
Background Soy and red clover isoflavones are controversial due to purported estrogenic
activity and possible effects on breast cancer. We conducted a systematic review of soy and …

Intravenous vitamin C and cancer: a systematic review

H Fritz, G Flower, L Weeks, K Cooley… - Integrative cancer …, 2014 - journals.sagepub.com
Background. Intravenous vitamin C (IVC) is a contentious adjunctive cancer therapy, widely
used in naturopathic and integrative oncology settings. We conducted a systematic review of …

Vitamin A in health care: Suppression of growth and induction of differentiation in cancer cells by vitamin A and its derivatives and their mechanisms of action

N Takahashi, D Saito, S Hasegawa, M Yamasaki… - Pharmacology & …, 2022 - Elsevier
Vitamin A is an important micro-essential nutrient, whose primary dietary source is retinyl
esters. In addition, β-carotene (pro-vitamin A) is a precursor of vitamin A contained in green …

Retinoids as chemo-preventive and molecular-targeted anti-cancer therapies

VO Hunsu, COB Facey, JZ Fields… - International Journal of …, 2021 - mdpi.com
Retinoic acid (RA) agents possess anti-tumor activity through their ability to induce cellular
differentiation. However, retinoids have not yet been translated into effective systemic …

Flax and breast cancer: a systematic review

G Flower, H Fritz, LG Balneaves… - Integrative cancer …, 2014 - journals.sagepub.com
Background. Flax is a food and dietary supplement commonly used for menopausal
symptoms. Flax is known for its lignan, α-linolenic acid, and fiber content, components that …

Oxidative stress and antioxidants in carcinogenesis and integrative therapy of cancer

L Milkovic, W Siems, R Siems… - Current pharmaceutical …, 2014 - ingentaconnect.com
Oxidative stress is often considered as a causative factor in carcinogenesis. In addition,
current knowledge recognizes oxidative stress as a mechanism by which various cancer …

Retinoids and their biological effects against cancer

F Alizadeh, A Bolhassani, A Khavari, SZ Bathaie… - International …, 2014 - Elsevier
There are more than 4000 natural and synthetic molecules structurally and/or functionally
related to vitamin A. Retinoids are a class of these compounds that are structurally …