FEBio FINESSE: An open-source finite element simulation approach to estimate in vivo heart valve strains using shape enforcement

DW Laurence, PM Sabin, AM Sulentic… - Annals of Biomedical …, 2024 - Springer
Purpose Finite element simulations are an enticing tool to evaluate heart valve function;
however, patient-specific simulations derived from 3D echocardiography are hampered by …

ADEPT: A Noninvasive Method for Determining Elastic Properties of Valve Tissue

W Wu, M Daneker, C Herz, H Dewey, JA Weiss… - arXiv preprint arXiv …, 2024 - arxiv.org
Valvular heart disease accounts for up to 20% of cardiac surgery in the United States.
Computer simulation of" virtual interventions" may inform optimal valve repair for a given …

Tricuspid Valve Edge-to-Edge Repair Simulations Are Highly Sensitive to Annular Boundary Conditions

CE Haese, V Dubey, M Mathur, AM Pouch… - Journal of the …, 2024 - Elsevier
Transcatheter edge-to-edge repair (TEER) simulations may provide insight into this novel
therapeutic technology and help optimize its use. However, because of the relatively short …

[HTML][HTML] Identifying heterogeneous micromechanical properties of biological tissues via physics-informed neural networks

W Wu, M Daneker, KT Turner, MA Jolley, L Lu - ArXiv, 2024 - ncbi.nlm.nih.gov
The heterogeneous micromechanical properties of biological tissues have profound
implications across diverse medical and engineering domains. However, identifying the full …

Leaflet remodeling reduces tricuspid valve function in a computational model

M Mathur, M Malinowski, T Jazwiec, TA Timek… - Journal of the …, 2024 - Elsevier
Tricuspid valve leaflets have historically been considered “passive flaps”. However, we have
recently shown that tricuspid leaflets actively remodel in sheep with functional tricuspid …

Effect of Parametric Variation of Chordae Tendineae Structure on Simulated Atrioventricular Valve Closure

NR Mangine, DW Laurence, PM Sabin, W Wu… - arXiv preprint arXiv …, 2024 - arxiv.org
Many approaches have been used to model chordae tendineae geometries in finite element
simulations of atrioventricular heart valves. Unfortunately, current" functional" chordae …