[HTML][HTML] Omicron variant (B. 1.1. 529) and its sublineages: What do we know so far amid the emergence of recombinant variants of SARS-CoV-2?

M Dhawan, ARA Saied, S Mitra, FA Alhumaydhi… - Biomedicine & …, 2022 - Elsevier
Since the start of the COVID-19 pandemic, numerous variants of SARS-CoV-2 have been
reported worldwide. The advent of variants of concern (VOCs) raises severe concerns amid …

Immune evasion of neutralizing antibodies by SARS-CoV-2 Omicron

L Wang, M Møhlenberg, P Wang, H Zhou - Cytokine & growth factor …, 2023 - Elsevier
Since its emergence at the end of 2019, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has caused the infection of more than 600 million people worldwide and has …

Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines

JE Bowen, A Addetia, HV Dang, C Stewart, JT Brown… - Science, 2022 - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of
concern comprises several sublineages, with BA. 2 and BA. 2.12. 1 having replaced the …

Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution

TN Starr, AJ Greaney, WW Hannon, AN Loes, K Hauser… - Science, 2022 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved variants with
substitutions in the spike receptor-binding domain (RBD) that affect its affinity for angiotensin …

Neutralizing antibody responses elicited by SARS-CoV-2 mRNA vaccination wane over time and are boosted by breakthrough infection

JP Evans, C Zeng, C Carlin, G Lozanski… - Science Translational …, 2022 - science.org
The waning efficacy of SARS-CoV-2 vaccines, combined with the continued emergence of
variants resistant to vaccine-induced immunity, has reignited debate over the need for …

Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness

F Obermeyer, M Jankowiak, N Barkas, SF Schaffner… - Science, 2022 - science.org
Repeated emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants with increased fitness underscores the value of rapid detection and characterization …

The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance

H Tegally, JE San, M Cotten, M Moir, B Tegomoh… - Science, 2022 - science.org
Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing
in Africa over the past year has led to a major increase in the number of sequences that …

Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine

RR Goel, MM Painter, KA Lundgreen, SA Apostolidis… - Cell, 2022 - cell.com
We examined antibody and memory B cell responses longitudinally for∼ 9–10 months after
primary 2-dose SARS-CoV-2 mRNA vaccination and 3 months after a 3rd dose. Antibody …

The Omicron variant BA. 1.1 presents a lower pathogenicity than B. 1 D614G and Delta variants in a feline model of SARS-CoV-2 infection

M Martins, GM do Nascimento, M Nooruzzaman… - Journal of …, 2022 - Am Soc Microbiol
ABSTRACT Omicron (B. 1.1. 529) is the most recent SARS-CoV-2 variant of concern, which
emerged in late 2021 and rapidly achieved global predominance by early 2022. In this …

Efficacy of mRNA-1273 and Novavax ancestral or BA. 1 spike booster vaccines against SARS-CoV-2 BA. 5 infection in nonhuman primates

NK Routhu, SD Stampfer, L Lai, A Akhtar, X Tong… - Science …, 2023 - science.org
Omicron SARS-CoV-2 variants escape vaccine-induced neutralizing antibodies and cause
nearly all current COVID-19 cases. Here, we compared the efficacy of three booster …