The immunology and immunopathology of COVID-19
Considerable research effort has been made worldwide to decipher the immune response
triggered upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections …
triggered upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections …
[HTML][HTML] The state of complement in COVID-19
Hyperactivation of the complement and coagulation systems is recognized as part of the
clinical syndrome of COVID-19. Here we review systemic complement activation and local …
clinical syndrome of COVID-19. Here we review systemic complement activation and local …
Persistent complement dysregulation with signs of thromboinflammation in active Long Covid
Long Covid is a debilitating condition of unknown etiology. We performed multimodal
proteomics analyses of blood serum from COVID-19 patients followed up to 12 months after …
proteomics analyses of blood serum from COVID-19 patients followed up to 12 months after …
[HTML][HTML] Pathophysiology of COVID-19-associated acute kidney injury
Although respiratory failure and hypoxaemia are the main manifestations of COVID-19,
kidney involvement is also common. Available evidence supports a number of potential …
kidney involvement is also common. Available evidence supports a number of potential …
[HTML][HTML] Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection
Neutralizing antibodies are known to have a crucial role in protecting against SARS-CoV-2
infection and have been suggested to be a useful correlate of protection for vaccine clinical …
infection and have been suggested to be a useful correlate of protection for vaccine clinical …
[HTML][HTML] Long COVID: pathophysiological factors and abnormalities of coagulation
S Turner, MA Khan, D Putrino, A Woodcock… - Trends in Endocrinology …, 2023 - cell.com
Acute COVID-19 infection is followed by prolonged symptoms in approximately one in ten
cases: known as Long COVID. The disease affects~ 65 million individuals worldwide. Many …
cases: known as Long COVID. The disease affects~ 65 million individuals worldwide. Many …
[HTML][HTML] Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19
A Bonaventura, A Vecchié, L Dagna… - Nature Reviews …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19) is a clinical syndrome caused by infection
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe …
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with severe …
[HTML][HTML] Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin
E Pretorius, M Vlok, C Venter, JA Bezuidenhout… - Cardiovascular …, 2021 - Springer
Background Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2)-induced
infection, the cause of coronavirus disease 2019 (COVID-19), is characterized by acute …
infection, the cause of coronavirus disease 2019 (COVID-19), is characterized by acute …
[HTML][HTML] Endothelial dysfunction and altered endothelial biomarkers in patients with post-COVID-19 syndrome and chronic fatigue syndrome (ME/CFS)
M Haffke, H Freitag, G Rudolf, M Seifert… - Journal of Translational …, 2022 - Springer
Background Fatigue, exertion intolerance and post-exertional malaise are among the most
frequent symptoms of Post-COVID Syndrome (PCS), with a subset of patients fulfilling …
frequent symptoms of Post-COVID Syndrome (PCS), with a subset of patients fulfilling …
[HTML][HTML] SARS-CoV-2-specific immune response and the pathogenesis of COVID-19
E Gusev, A Sarapultsev, L Solomatina… - International journal of …, 2022 - mdpi.com
The review aims to consolidate research findings on the molecular mechanisms and
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …
virulence and pathogenicity characteristics of coronavirus disease (COVID-19) causative …