Global epidemiology of stroke and access to acute ischemic stroke interventions

V Saini, L Guada, DR Yavagal - Neurology, 2021 - AAN Enterprises
Purpose of the Review To provide an up-to-date review of the incidence of stroke and large
vessel occlusion (LVO) around the globe, as well as the eligibility and access to IV …

Ischemic stroke

SK Feske - The American journal of medicine, 2021 - Elsevier
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Tenecteplase for ischemic stroke at 4.5 to 24 hours without thrombectomy

Y Xiong, BCV Campbell, LH Schwamm… - … England Journal of …, 2024 - Mass Medical Soc
Background Tenecteplase is an effective thrombolytic agent for eligible patients with stroke
who are treated within 4.5 hours after the onset of stroke. However, data regarding the …

Reteplase versus alteplase for acute ischemic stroke

S Li, HQ Gu, H Li, X Wang, A Jin, S Guo… - … England Journal of …, 2024 - Mass Medical Soc
Background Alteplase is the standard agent used in early reperfusion therapy, but
alternative thrombolytic agents are needed. The efficacy and safety of reteplase as …

Tenecteplase versus alteplase in acute ischaemic cerebrovascular events (TRACE-2): a phase 3, multicentre, open-label, randomised controlled, non-inferiority trial

Y Wang, S Li, Y Pan, H Li, MW Parsons, BCV Campbell… - The Lancet, 2023 - thelancet.com
Background There is increasing interest in replacing alteplase with tenecteplase as the
preferred thrombolytic treatment for patients with acute ischaemic stroke. We aimed to …

European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke

E Berge, W Whiteley, H Audebert… - European stroke …, 2021 - journals.sagepub.com
Intravenous thrombolysis is the only approved systemic reperfusion treatment for patients
with acute ischaemic stroke. These European Stroke Organisation (ESO) guidelines provide …

Neuroinflammation in cerebral ischemia and ischemia/reperfusion injuries: from pathophysiology to therapeutic strategies

A Jurcau, A Simion - International journal of molecular sciences, 2021 - mdpi.com
Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications

Q Tuo, S Zhang, P Lei - Medicinal research reviews, 2022 - Wiley Online Library
Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …

Noncontrast computed tomography vs computed tomography perfusion or magnetic resonance imaging selection in late presentation of stroke with large-vessel …

TN Nguyen, M Abdalkader, S Nagel… - JAMA …, 2022 - jamanetwork.com
Importance Advanced imaging for patient selection in mechanical thrombectomy is not
widely available. Objective To compare the clinical outcomes of patients selected for …

Management of acute ischemic stroke

F Herpich, F Rincon - Critical care medicine, 2020 - journals.lww.com
Objectives: Concise “synthetic” review of the state of the art of management of acute
ischemic stroke. Data Sources: Available literature on PubMed. Study Selection: We …