Rice functional genomics: decades' efforts and roads ahead

R Chen, Y Deng, Y Ding, J Guo, J Qiu, B Wang… - Science China Life …, 2022 - Springer
Rice (Oryza sativa L.) is one of the most important crops in the world. Since the completion of
rice reference genome sequences, tremendous progress has been achieved in …

Defended to the nines: 25 years of resistance gene cloning identifies nine mechanisms for R protein function

J Kourelis, RAL Van Der Hoorn - The Plant Cell, 2018 - academic.oup.com
Plants have many, highly variable resistance (R) gene loci, which provide resistance to a
variety of pathogens. The first R gene to be cloned, maize (Zea mays) Hm1, was published …

NLRs guard metabolism to coordinate pattern-and effector-triggered immunity

K Zhai, DI Liang, H Li, F Jiao, B Yan, J Liu, Z Lei… - Nature, 2022 - nature.com
Pattern-triggered immunity (PTI) and effector-triggered immunity (ETI) in plants enable them
to respond to pathogens by activating the production of defence metabolites that orchestrate …

Intracellular innate immune surveillance devices in plants and animals

JDG Jones, RE Vance, JL Dangl - Science, 2016 - science.org
BACKGROUND Pathogens cause agricultural devastation and huge economic losses. Up to
30% of our crops are lost before or after harvest to pathogens and pests, wasting water and …

NOD-like receptor-mediated plant immunity: from structure to cell death

IML Saur, R Panstruga, P Schulze-Lefert - Nature Reviews Immunology, 2021 - nature.com
Animal and plant immune systems use intracellular nucleotide-binding oligomerization
domain (NOD)-like receptors (NLRs) to detect pathogens, resulting in the activation of …

[HTML][HTML] A species-wide inventory of NLR genes and alleles in Arabidopsis thaliana

AL Van de Weyer, F Monteiro, OJ Furzer, MT Nishimura… - Cell, 2019 - cell.com
Infectious disease is both a major force of selection in nature and a prime cause of yield loss
in agriculture. In plants, disease resistance is often conferred by nucleotide-binding leucine …

Plant NLR diversity: the known unknowns of pan-NLRomes

AC Barragan, D Weigel - The Plant Cell, 2021 - academic.oup.com
Plants and pathogens constantly adapt to each other. As a consequence, many members of
the plant immune system, and especially the intracellular nucleotide-binding site leucine …

Genetic modification to improve disease resistance in crops

HP Van Esse, TL Reuber, D van der Does - New Phytologist, 2020 - Wiley Online Library
Plant pathogens are a significant challenge in agriculture despite our best efforts to combat
them. One of the most effective and sustainable ways to manage plant pathogens is to use …

CRISPR crops: plant genome editing toward disease resistance

T Langner, S Kamoun, K Belhaj - Annual review of …, 2018 - annualreviews.org
Genome editing by sequence-specific nucleases (SSNs) has revolutionized biology by
enabling targeted modifications of genomes. Although routine plant genome editing …

NLR receptors in plant immunity: making sense of the alphabet soup

MP Contreras, D Lüdke, H Pai, AA Toghani… - EMBO …, 2023 - embopress.org
Plants coordinately use cell‐surface and intracellular immune receptors to perceive
pathogens and mount an immune response. Intracellular events of pathogen recognition are …