The impact of ACE and ACE2 gene polymorphisms in pulmonary diseases including COVID-19

I Gintoni, M Adamopoulou, C Yapijakis - in vivo, 2022 - iv.iiarjournals.org
Chronic and acute respiratory diseases pose a major problem for public health worldwide
due to the high morbidity and mortality rates, while treatment options remain mostly …

Updates on the COPD gene list

Y Bossé - International journal of chronic obstructive pulmonary …, 2012 - Taylor & Francis
A genetic contribution to develop chronic obstructive pulmonary disease (COPD) is well
established. However, the specific genes responsible for enhanced risk or host differences …

Does genetic predisposition contribute to the exacerbation of COVID-19 symptoms in individuals with comorbidities and explain the huge mortality disparity between …

N Yamamoto, R Yamamoto, Y Ariumi… - International Journal of …, 2021 - mdpi.com
The elderly and patients with several comorbidities experience more severe cases of
coronavirus disease 2019 (COVID-19) than healthy patients without underlying medical …

ACE gene I/D polymorphism and arterial hypertension in patients with COPD

M Marushchak, K Maksiv, I Krynytska - Pneumologia, 2019 - sciendo.com
Background: Cardiovascular diseases (CVDs) are common in people with chronic
obstructive pulmonary disease (COPD), and their presence is associated with an increased …

ACE gene polymorphism is associated with COPD and COPD with pulmonary hypertension: a meta-analysis

Y Ma, X Tong, Y Liu, S Liu, H Xiong… - International Journal of …, 2018 - Taylor & Francis
Purpose Angiotensin-converting enzyme (ACE) gene I/D polymorphism has been studied in
relation to the susceptibility to COPD and COPD with pulmonary hypertension (PH) with …

[HTML][HTML] Common intronic D variant of ACE gene is associated with endothelial dysfunction in COPD

NA Kuzubova, AB Chukhlovin, EB Morozova… - Respiratory …, 2013 - Elsevier
Background Pathogenesis of chronic obstructive lung disease (COPD) includes primary
inflammatory events, multiple vascular reactions, remodeling of bronchial and vascular …

[PDF][PDF] Impact of I/D polymorphism of ACE gene on risk of development and course of chronic obstructive pulmonary disease

R Mlak, I Homa-Mlak, T Powrózek… - Archives of Medical …, 2016 - termedia.pl
Results: In the generalized linear model (GLZ) analysis of the influence of selected factors
on presence of COPD we found a significant independent effect for male sex (repeatedly …

Genetic Polymorphism of Angiotensin‐Converting Enzyme and Chronic Obstructive Pulmonary Disease Risk: An Updated Meta‐Analysis

SW Kang, SK Kim, JH Chung, HJ Jung… - BioMed research …, 2016 - Wiley Online Library
The relationship between polymorphism of the angiotensin I converting enzyme (ACE) gene
and chronic obstructive pulmonary disease (COPD) has been examined in many previous …

[HTML][HTML] Angiotensin-converting enzyme polymorphism affects outcome of local Chinese with acute lung injury

XM Lu, GJ Chen, Y Yang, HB Qiu - Respiratory medicine, 2011 - Elsevier
INTRODUCTION: Acute Lung Injury (ALI) with genetic predisposition is fatal. Relationship
between angiotensin-converting enzyme insertion/deletion (ACE I/D) polymorphism and the …

Association of angiotensin-converting enzyme gene I/D polymorphism with chronic obstructive pulmonary disease: a meta-analysis

G Xu, G Fan, Y Sun, L Yu, S Wu… - Journal of the Renin …, 2018 - journals.sagepub.com
Objectives: We conducted a meta-analysis of published studies on the angiotensin-
converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism associated with the …