[HTML][HTML] The role of NF-κB in breast cancer initiation, growth, metastasis, and resistance to chemotherapy

E Pavitra, J Kancharla, VK Gupta, K Prasad… - Biomedicine & …, 2023 - Elsevier
Breast cancer (BC) is the second most fatal disease and is the prime cause of cancer allied
female deaths. BC is caused by aberrant tumor suppressor genes and oncogenes regulated …

[HTML][HTML] Ionizing radiation-induced circulatory and metabolic diseases

S Tapio, MP Little, JC Kaiser, N Impens… - Environment …, 2021 - Elsevier
Risks to health are the prime consideration in all human situations of ionizing radiation
exposure and therefore of relevance to radiation protection in all occupational, medical, and …

Cardiac radiotherapy induces electrical conduction reprogramming in the absence of transmural fibrosis

DM Zhang, R Navara, T Yin, J Szymanski… - Nature …, 2021 - nature.com
Cardiac radiotherapy (RT) may be effective in treating heart failure (HF) patients with
refractory ventricular tachycardia (VT). The previously proposed mechanism of radiation …

Heart in space: effect of the extraterrestrial environment on the cardiovascular system

RL Hughson, A Helm, M Durante - Nature Reviews Cardiology, 2018 - nature.com
National space agencies and private corporations aim at an extended presence of humans
in space in the medium to long term. Together with currently suboptimal technology …

Effects of ionizing radiation on the heart

M Boerma, V Sridharan, XW Mao, GA Nelson… - … Research/Reviews in …, 2016 - Elsevier
This article provides an overview of studies addressing effects of ionizing radiation on the
heart. Clinical studies have identified early and late manifestations of radiation-induced …

Long-term spaceflight and the cardiovascular system

NA Vernice, C Meydan, E Afshinnekoo… - Precision Clinical …, 2020 - academic.oup.com
While early investigations into the physiological effects of spaceflight suggest the body's
ability to reversibly adapt, the corresponding effects of long-term spaceflight (> 6 months) are …

Myocardial disease and long-distance space travel: Solving the radiation problem

M Meerman, TCL Bracco Gartner… - Frontiers in …, 2021 - frontiersin.org
Radiation-induced cardiovascular disease is a well-known complication of radiation
exposure. Over the last few years, planning for deep space missions has increased interest …

Application of radiation omics in the development of adverse outcome pathway networks: an example of radiation-induced cardiovascular disease

O Azimzadeh, S Moertl, R Ramadan… - … Journal of Radiation …, 2022 - Taylor & Francis
Background Epidemiological studies have indicated that exposure of the heart to doses of
ionizing radiation as low as 0.5 Gy increases the risk of cardiac morbidity and mortality with …

Radiation-induced cardiovascular disease: mechanisms and importance of linear energy transfer

CB Sylvester, J Abe, ZS Patel… - Frontiers in …, 2018 - frontiersin.org
Radiation therapy (RT) in the form of photons and protons is a well-established treatment for
cancer. More recently, heavy charged particles have been used to treat radioresistant and …

Consequences of space radiation on the brain and cardiovascular system

CM Davis, AR Allen, DE Bowles - Journal of Environmental …, 2021 - Taylor & Francis
Staying longer in outer space will inevitably increase the health risks of astronauts due to the
exposures to galactic cosmic rays and solar particle events. Exposure may pose a significant …