Advances in sperm analysis: techniques, discoveries and applications

C Dai, Z Zhang, G Shan, LT Chu, Z Huang… - Nature Reviews …, 2021 - nature.com
Infertility affects one in six couples worldwide, and fertility continues to deteriorate globally,
partly owing to a decline in semen quality. Sperm analysis has a central role in diagnosing …

Influence of risk factors for male infertility on sperm protein composition

M Bisconti, JF Simon, S Grassi, B Leroy… - International Journal of …, 2021 - mdpi.com
Male infertility is a common health problem that can be influenced by a host of lifestyle risk
factors such as environment, nutrition, smoking, stress, and endocrine disruptors. These …

The simultaneous administration of microplastics and cadmium alters rat testicular activity and changes the expression of PTMA, DAAM1 and PREP

M Venditti, M Ben Hadj Hassine, I Messaoudi… - Frontiers in Cell and …, 2023 - frontiersin.org
This paper confirms the damaging effects produced by MP and Cd on testicular activity in the
rat. Oral treatment with both chemicals resulted in testicular damage, documented by …

Whole exome sequencing and in silico analysis of human Sertoli in patients with non-obstructive azoospermia

H Azizi, D Hashemi Karoii, T Skutella - International Journal of Molecular …, 2022 - mdpi.com
Non-obstructive azoospermia (NOA) is a serious cause of male infertility. The Sertoli cell
responds to androgens and takes on roles supporting spermatogenesis, which may cause …

CAMSAP1 role in orchestrating structure and dynamics of manchette microtubule minus-ends impacts male fertility during spermiogenesis

W Hu, R Zhang, H Xu, Y Li, X Yang… - Proceedings of the …, 2023 - National Acad Sciences
The manchette is a crucial transient structure involved in sperm development, with its
composition and regulation still not fully understood. This study focused on investigating the …

Haploid male germ cells—the Grand Central Station of protein transport

C Pleuger, MS Lehti, JEM Dunleavy… - Human …, 2020 - academic.oup.com
BACKGROUND The precise movement of proteins and vesicles is an essential ability for all
eukaryotic cells. Nowhere is this more evident than during the remarkable transformation …

Testicular localization and potential function of vimentin positive cells during spermatogonial differentiation stages

A Niazi Tabar, H Azizi, D Hashemi Karoii, T Skutella - Animals, 2022 - mdpi.com
Simple Summary Spermatogonia stem cells (SSCs) in the testis are responsible for
transmitting genetic information to subsequent generations. During the differentiation of …

Testis‐specific serine kinase 3 is required for sperm morphogenesis and male fertility

K Nozawa, TX Garcia, K Kent, M Leng, A Jain… - …, 2023 - Wiley Online Library
Background The importance of phosphorylation in sperm during spermatogenesis has not
been pursued extensively. Testis‐specific serine kinase 3 (Tssk3) is a conserved gene, but …

Importance of the androgen receptor signaling in gene transactivation and transrepression for pubertal maturation of the testis

NY Edelsztein, RA Rey - Cells, 2019 - mdpi.com
Androgens are key for pubertal development of the mammalian testis, a phenomenon that is
tightly linked to Sertoli cell maturation. In this review, we discuss how androgen signaling …

Sperm differentiation: the role of trafficking of proteins

ME Teves, ERS Roldan, D Krapf, JF Strauss III… - International journal of …, 2020 - mdpi.com
Sperm differentiation encompasses a complex sequence of morphological changes that
takes place in the seminiferous epithelium. In this process, haploid round spermatids …