Antimicrobial agents have eradicated many infectious diseases and significantly improved
our living environment. However, abuse of antimicrobial agents has accelerated the …

Human civilization has witnessed the use of materials-derived from biomolecules of plants
and animal origin for biomedical applications since ancient era. In recent years, precision …

Peptide-based supramolecular assemblies are a promising class of nanomaterials with
important biomedical applications, specifically in drug delivery and tissue regeneration …

We report the structure–activity relationship in the antimicrobial activity of linear and
branched poly (ethylene imine) s (L‐and B‐PEIs) with a range of molecular weights …

Brilacidin (PMX30063) has shown potent bactericidal activity against drug-resistant and-
susceptible strains of multiple Gram-negative and Gram-positive pathogens. In this study, we …

With the alarming burden of antibiotic resistance, antimicrobial peptides (AMPs) seem to be
novel antimicrobial alternatives for infection treatment due to their rapid broad-spectrum …

Clinically, antibiotics are widely used to treat infectious diseases; however, excessive drug
abuse and overuse exacerbate the prevalence of drug-resistant bacterial pathogens …

Over the past decade, foldamers have progressively emerged as useful architectures to
mimic secondary structures of proteins. Peptidic foldamers, consisting of various amino acid …

Infectious diseases continue to be one of the major contributors to human morbidity. The
rapid rate at which pathogenic microorganisms have developed resistance against frontline …

Therapeutics targeting Gram-negative bacteria have the challenge of overcoming a
formidable outer membrane (OM) barrier. Here, we characterize the action of SPR741, a …