Traditional dietary recommendations for patients with chronic kidney disease (CKD) focus
on the quantity of nutrients consumed. Without appropriate dietary counselling, these …

With the advances in biomedical technologies, natural products have attracted substantial
public attention in the area of drug discovery. Flavonoids are a class of active natural …

Flavonoids are natural polyphenolic compounds which are included in a panoply of drugs
and used to treat and/or manage human ailments such as metabolic, cardiovascular …

Acute kidney injury (AKI) is a common clinical problem, characterized by a sudden loss of
renal function, a high risk of death, and the eventual development of renal fibrosis and renal …

Chronic kidney disease (CKD) is a progressive systemic disease, which changes the
function and structure of the kidneys irreversibly over months or years. The final common …

Pomegranate (Punica granatum) acts as a therapeutic fruit possessing different bioactive
compounds. Different compartments of pomegranate (P. granatum) like seed, peel, juice and …

Simple Summary Increased stress is often observed in patients with kidney diseases,
contributing to renal injury progression. Flavonoids are naturally occurring plant compounds …

Background Sepsis is a life-threatening condition caused by a dysregulated host response
to infection. Several studies have indicated that flavonoids exhibit a wide variety of biological …

Fibrosis is a hallmark of progressive kidney diseases. The overexpression of profibrotic
cytokine, namely transforming growth factor β (TGF-β) due to excessive inflammation and …

Endoplasmic reticulum (ER) stress plays a key role in cadmium chloride (CdCl2)-induced
nephrotoxicity. Sirtuin-1 (SIRT1) is a potent inhibitor of ER stress. In this study, we examined …