I. Executive Summary Background The 5 years since the publication of the first International
Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR‐RS) has witnessed …

Contributing Authors Isam Alobid, MD, PhD1, Nithin D. Adappa, MD2, Henry P. Barham,
MD3, Thiago Bezerra, MD4, Nadieska Caballero, MD5, Eugene G. Chang, MD6, Gaurav …

Objective In the era of SARS-CoV-2, the risk of infectious airborne aerosol generation during
otolaryngologic procedures has been an area of increasing concern. The objective of this …

Information for Category 1 CME Credit Credit can now be obtained, free for a limited time, by
reading the review articles in this issue. Please note the following instructions. Method of …

Background Appropriate indications for endoscopic sinus surgery (ESS) for chronic
rhinosinusitis (CRS) are currently poorly defined. The lack of clear surgical indications for …

Objectives The aim of this study was to investigate the surgical revision rate in patients with
chronic rhinosinusitis (CRS) in the UK CRS Epidemiology Study (CRES). Previous evidence …

Primary immunodeficiency disorders (PIDs) are caused by 1 or more defects of the immune
system. Patients are more likely to experience recurrent and/or severe infections and tend to …

Nasal obstruction (NO) is defined as the subjective perception of discomfort or difficulty in
the passage of air through the nostrils. It is a common reason for consultation in primary and …

Abstract Purpose of Review Chronic rhinosinusitis (CRS) has a significant negative impact
on quality of life (QoL). Surgical treatment of CRS is indicated when medical therapy fails to …

Background The currently accepted treatment paradigm of treating chronic rhinosinusitis
(CRS) first with appropriate medical therapy (AMT) and then with surgery if patients are …