Studies using animal models of adolescent exposure to alcohol, nicotine, cannabinoids, and
the stimulants cocaine, 3, 4-methylenedioxymethampethamine and methamphetamine have …

Sensation-seeking (SS) is a personality trait that refers to individual differences in motivation
for intense and unusual sensory experiences. It describes a facet of human behaviour that …

Cocaine is one of the most widely used and increasingly popular illicit psychoactive drugs.
Unlike other commonly used substances of abuse, cocaine has no pharmacological …

Social behaviour is disturbed in many substance abuse and psychiatric disorders. Given the
consensus that social behaviours of lower mammals may help to understand some human …

Novelty seeking (NS), defined as a tendency to pursue novel and intense emotional
sensations and experiences, is one of the most relevant individual factors predicting drug …

Repetitive drug/ethanol (EtOH) binge-like consumption during pre-addictive stages favors a
transition to addiction in vulnerable organisms. Experimental evidence points to the …

The relationship between stress and drug use is well demonstrated. Stress-induced by
repeated social defeat (RSD) enhances the conditioned place preference (CPP) induced by …

Background Ethanol (EtOH) binge drinking is an increasingly common behavior among
teenagers that induces long-lasting neurobehavioral alterations in adulthood. An early …

Numerous studies report that social defeat stress alters dopamine (DA) neurotransmission in
several areas of the brain. Alterations of the mesolimbic dopaminergic pathway are believed …

Social stress modifies the activity of brain areas involved in the rewarding effects of
psychostimulants, inducing neuroadaptations in the dopaminergic mesolimbic system and …