Recent advances on the role of ATGL in cancer

R Zhang, J Meng, S Yang, W Liu, L Shi, J Zeng… - Frontiers in …, 2022 - frontiersin.org
The hypoxic state of the tumor microenvironment leads to reprogramming lipid metabolism
in tumor cells. Adipose triglyceride lipase, also known as patatin-like phospholipase …

Visualizing macrophage phenotypes and polarization in diseases: from biomarkers to Molecular Probes

D Ni, H Zhou, P Wang, F Xu, C Li - Phenomics, 2023 - Springer
Macrophage is a kind of immune cell and performs multiple functions including pathogen
phagocytosis, antigen presentation and tissue remodeling. To fulfill their functionally distinct …

Lipid droplets as cell fate determinants in skeletal muscle

J Chen, JF Markworth, C Ferreira, C Zhang… - Trends in Endocrinology …, 2024 - cell.com
Lipid droplets (LDs) are dynamic organelles that communicate with other cellular
components to orchestrate energetic homeostasis and signal transduction. In skeletal …

Inflammaging and fatty acid oxidation in monocytes and macrophages

V Kruglov, IH Jang, CD Camell - Immunometabolism, 2024 - journals.lww.com
Fatty acid oxidation (FAO), primarily known as β-oxidation, plays a crucial role in breaking
down fatty acids within mitochondria and peroxisomes to produce cellular energy and …

Unveiling the Structure‐Fluorogenic Property Relationship of Seoul‐Fluor‐Derived Bioorthogonal Tetrazine Probes

H Son, D Kim, S Kim, WG Byun… - Angewandte Chemie …, 2024 - Wiley Online Library
Tetrazine (Tz)‐embedded fluorescent probes, known for their fluorogenicity following
bioorthogonal inverse electron‐demand Diels‐Alder (iEDDA) reactions, are extensively …

Silencing endomucin in bone marrow sinusoids improves hematopoietic stem and progenitor cell homing during transplantation

Y Li, M Ren, H Li, Z Zhang, K Yuan, Y Huang… - Stem Cells, 2024 - academic.oup.com
Efficient homing of infused hematopoietic stem and progenitor cells (HSPCs) into the bone
marrow (BM) is the prerequisite for successful hematopoietic stem cell transplantation …

[HTML][HTML] Nano Delivery System for Atherosclerosis

Z Rong, X He, T Fan, H Zhang - Journal of Functional Biomaterials, 2024 - mdpi.com
Atherosclerosis, a pathological process propelled by inflammatory mediators and lipids, is a
principal contributor to cardiovascular disease incidents. Currently, drug therapy, the primary …

Fatty acid synthesis is indispensable for Kupffer cells to eliminate bacteria in ALD progression

L Xie, B Wu, Y Fan, Y Tao, X Jiang, Q Li… - Hepatology …, 2024 - journals.lww.com
Background: Dysregulated fatty acid metabolism is closely linked to the development of
alcohol-associated liver disease (ALD). KCs, which are resident macrophages in the liver …

PHYSIOLOGICALLY INDUCED HIGH GAUSSIAN CURVATURE DRIVES NUCLEAR LAMINA RUPTURE AND CYTOSKELETAL DISPLACEMENT—CONTRIBUTING …

M Tobin - 2023 - repository.upenn.edu
Interphase nuclear rupture is a known driver of DNA damage and may ultimately lead to
genetic instability promoting cell dysfunction and cancer progression. As the structural …