Over half a century has passed since interferons (IFNs) were discovered and shown to
inhibit virus infection in cultured cells. Since then, researchers have steadily brought to light …

Since the discovery of interferon 50years ago a great deal of progress has been made in
understanding how interferons work and how and why they are induced. Key factors in …

Productive herpesvirus infection requires a profound, time-controlled remodeling of the viral
transcriptome and proteome. To gain insights into the genomic architecture and gene …

Recent studies have identified circular RNAs (circRNAs) expressed from the Epstein-Barr
virus (EBV) and Kaposi's sarcoma herpesvirus (KSHV) human DNA tumor viruses. To gain …

Kaposi's sarcoma-associated herpesvirus (KSHV) is the most recently discovered human
herpesvirus. It is the aetiological agent of Kaposi's sarcoma (KS), a tumour frequently …

Herpesvirus infection leads to the rapid induction of an innate immune response. A central
aspect of this host response is the production and secretion of type I interferon. The current …

To efficiently establish a persistent infection, Kaposi's sarcoma-associated herpesvirus
(KSHV; also known as HHV8) dedicates a large amount of its coding potential to produce …

TIA-1 positive stress granules (SG) represent the storage sites of stalled mRNAs and are
often associated with the cellular antiviral response. In this report, we provide evidence that …

Human herpesvirus 8 (HHV-8) encodes four viral interferon regulatory factors (vIRFs) that
target cellular IRFs and/or other innate-immune and stress signaling regulators and …

Simple Summary Primary effusion lymphoma (PEL) is a rare B-cell lymphoma with a
particularly aggressive course. This disease usually affects the variably …