A comprehensive review on immunogen and immune-response proteins of SARS-CoV-2 and their applications in prevention, diagnosis, and treatment of COVID-19

D Zhang, D Kukkar, KH Kim, P Bhatt - International Journal of Biological …, 2024 - Elsevier
Exposure to severe acute respiratory syndrome-corona virus-2 (SARS-CoV-2) prompts
humoral immune responses in the human body. As the auxiliary diagnosis of a current …

Egg yolk antibody for passive immunization: status, challenges, and prospects

H Wang, Q Zhong, J Lin - Journal of Agricultural and Food …, 2023 - ACS Publications
The immunoglobulin Y (IgY) derived from hyperimmune egg yolk is a promising passive
immune agent to combat microbial infections in humans and livestock. Numerous studies …

IgY antibodies as Biotherapeutics in Biomedicine

D León-Núñez, MF Vizcaíno-López, M Escorcia… - Antibodies, 2022 - mdpi.com
Since the discovery of antibodies by Emil Von Behring and Shibasaburo Kitasato during the
19th century, their potential for use as biotechnological reagents has been exploited in …

Preclinical assessment of IgY antibodies against recombinant SARS-CoV-2 RBD protein for prophylaxis and post-infection treatment of COVID-19

A Agurto-Arteaga, A Poma-Acevedo… - Frontiers in …, 2022 - frontiersin.org
Within the framework of the current COVID-19 pandemic, there is a race against time to find
therapies for the outbreak to be controlled. Since vaccines are still tedious to develop and …

Are hamsters a suitable model for evaluating the immunogenicity of RBD-based anti-COVID-19 subunit vaccines?

IA Merkuleva, DN Shcherbakov, MB Borgoyakova… - Viruses, 2022 - mdpi.com
Currently, SARS-CoV-2 spike receptor-binding-domain (RBD)-based vaccines are
considered one of the most effective weapons against COVID-19. During the first step of …

Antiviral immunoglobulins of chicken egg yolk for potential prevention of SARS-CoV-2 infection

E Ravlo, L Evensen, G Sanson, S Hildonen, A Ianevski… - Viruses, 2022 - mdpi.com
Background: Some viruses cause outbreaks, which require immediate attention.
Neutralizing antibodies could be developed for viral outbreak management. However, the …

[HTML][HTML] Evaluating the Protective Role of Intranasally Administered Avian-Derived IgY Against SARS-CoV-2 in Syrian Hamster Models

M Madai, D Hanna, R Hetényi, F Földes, Z Lanszki… - Vaccines, 2024 - mdpi.com
Background/Objectives: The ongoing COVID-19 pandemic has underscored the need for
alternative prophylactic measures, particularly for populations for whom vaccines may not be …

Egg-yolk antibodies raised to VacJ passively immunize mice against Acinetobacter baumannii pneumonia in a neutropenic murine model

A Sharifi, I Rasooli, A Jahangiri - Process Biochemistry, 2023 - Elsevier
There is no effective antibiotic against emerging highly resistant Acinetobacter baumannii
strains, and there is a need for alternative treatment options. Egg-yolk antibodies (IgYs) are …

Development of polyclonal chicken egg yolk immunoglobulin Y (IgY) antibodies targeting SARS-CoV-2 multi-epitope antigen

A Fibriani, K Naisanu, N Yamahoki… - Journal of Virological …, 2025 - Elsevier
Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is the primary cause of the
Coronavirus disease 2019 (COVID-19) pandemic, which affects millions of people …

Novel extraction technologies and potential applications of egg yolk proteins

L Gu, Y Liu, W Zhang, J Li, C Chang, Y Su… - Food Science and …, 2023 - Springer
The high nutritional value and diverse functional properties of egg yolk proteins have led to
its widespread use in the fields of food, medicine, and cosmetics. Various extraction …