Fibrosis is the abnormal deposition of extracellular matrix, which can lead to organ
dysfunction, morbidity, and death. The disease burden caused by fibrosis is substantial, and …

Tissue macrophages rapidly recognize and engulf apoptotic cells. These events require the
display of so-called eat-me signals on the apoptotic cell surface, the most fundamental of …

The immunogenicity of cancer cells is an emerging determinant of anti‐cancer
immunotherapy. Beyond developing immunostimulatory regimens like dendritic cell‐based …

Uncontrolled inflammation is a leading cause of many clinically relevant diseases. Current
therapeutic strategies focus mainly on immunosuppression rather than on the mechanisms …

Alterations of cell death pathways, including apoptosis and the neutrophil specific kind of
death called NETosis, can represent a potential source of autoantigens. Defects in the …

Phosphatidylserine recognition receptors are a highly diverse set of receptors grouped by
their ability to recognize the 'eat‐me'signal phosphatidylserine on apoptotic cells. Most of the …

The major goal of radiotherapy is the induction of tumor cell death. Additionally, radiotherapy
can function as in situ cancer vaccination by exposing tumor antigens and providing …

Rationale: After myocardial ischemic injury, improper phagocytic clearance of dying cardiac
cells and the ensuing lack of inflammation resolution results in adverse cardiac remodeling …

Mesenchymal stromal cells (MSCs) are used for ameliorating liver fibrosis and aiding liver
regeneration after cirrhosis; Here, we analyzed the therapeutic potential of small …

For many decades, glucocorticoids have been widely used as the gold standard treatment
for inflammatory conditions. Unfortunately, their clinical use is limited by severe adverse …