Management of colon cancer: resource-stratified guidelines from the Asian Oncology Summit 2012
Colon cancer is seen with increasing frequency in the Asia-Pacific region, and it is one of the
most important causes of cancer mortality worldwide. This article reviews the available …
most important causes of cancer mortality worldwide. This article reviews the available …
[HTML][HTML] Epiregulin gene expression as a biomarker of benefit from cetuximab in the treatment of advanced colorectal cancer
DJ Jonker, CS Karapetis, C Harbison… - British journal of …, 2014 - nature.com
Background: Anti-EGFR antibody, cetuximab, improves overall survival (OS) in K-ras wild-
type chemotherapy–refractory colorectal cancer. Epidermal growth factor receptor ligand …
type chemotherapy–refractory colorectal cancer. Epidermal growth factor receptor ligand …
[HTML][HTML] The use of COLD-PCR and high-resolution melting analysis improves the limit of detection of KRAS and BRAF mutations in colorectal cancer
I Mancini, C Santucci, R Sestini, L Simi… - The Journal of Molecular …, 2010 - Elsevier
Fast and reliable tests to detect mutations in human cancers are required to better define
clinical samples and orient targeted therapies. KRAS mutations occur in 30–50% of …
clinical samples and orient targeted therapies. KRAS mutations occur in 30–50% of …
[HTML][HTML] Advantages of the net benefit regression framework for trial-based economic evaluations of cancer treatments: an example from the Canadian Cancer Trials …
Background Economic evaluations commonly accompany trials of new treatments or
interventions; however, regression methods and their corresponding advantages for the …
interventions; however, regression methods and their corresponding advantages for the …
[HTML][HTML] Patient and work flow and costs associated with staff time and facility usage at a comprehensive cancer centre in Quebec, Canada–a time and motion study
GA Shinder, PE Paradis, M Posman… - BMC health services …, 2012 - Springer
Background Mapping patient and work flow and cost analysis studies can help determine
the most efficient and cost effective way of providing health services while still maintaining …
the most efficient and cost effective way of providing health services while still maintaining …
Dynamic Chemotherapy Scheduling for Metastatic Colorectal Cancer Patients: Assessments and Improvements
I Toumazis - 2015 - search.proquest.com
Colorectal cancer (CRC) is the third most common and second deadliest type of cancer
affecting both sexes. Patients with late-stage CRC undergo sequential chemotherapy …
affecting both sexes. Patients with late-stage CRC undergo sequential chemotherapy …
High drug costs limit cetuximab's utility
N Mittmann - PharmacoEconomics & Outcomes News, 2009 - Springer
Researchers from the National Cancer Institute of Canada Clinical Trials Group conclude
that it would not be efficient, from a healthcare system perspective, to fund cetuximab for all …
that it would not be efficient, from a healthcare system perspective, to fund cetuximab for all …