Neonatal seizures occur in their majority in close temporal relation to an acute brain injury or
systemic insult, and are accordingly defined as acute symptomatic or provoked seizures …

Introduction Nearly one-third of all infants with epilepsy develop drug-resistant epilepsy.
Although epilepsy surgery is a well-established therapy across all age groups, there might …

Objective We aimed to evaluate determinants of functional outcome after pediatric
hemispherotomy in a large and recent multicenter cohort. Methods We retrospectively …

In addition to the primary aim of seizure freedom, a key secondary aim of pediatric epilepsy
surgery is to stabilize and, potentially, optimize cognitive development. Although the efficacy …

Objective This systematic review aimed to assess the intellectual outcome of children who
underwent surgery for epilepsy. Methods A systematic review of electronic databases was …

Objectives The manuscript serves as an update on the current management practices for
infantile spasm syndrome (ISS). It includes a detailed summary of the level of current …

Neuropsychological impairments are common in children with drug-resistant epilepsy. It has
been proposed that epilepsy surgery may alleviate these impairments by providing seizure …

Regression in children with epilepsy may involve loss of cognitive abilities, failure to
progress or a slowing of developmental trajectory. A few seizures do not lead to regression …

Epilepsy surgery is the most effective treatment option for children with refractory focal
lesional epilepsy, with seizure-freedom rates exceeding 70% two years after surgery …

Epilepsy surgery can achieve seizure freedom in selected pediatric candidates, but reliable
postsurgical predictors of seizure freedom are missing. High frequency oscillations (HFO) in …