Over 35 years ago the cell biology community was introduced to connexins as the subunit
employed to assemble semicrystalline clusters of intercellular channels that had been well …

Preclinical studies have identified glial cells as pivotal players in the genesis and
maintenance of neuropathic pain after nerve injury associated with diabetes, chemotherapy …

Connexin hemichannels were identified as the first members of the eukaryotic large-pore
channel family that mediate permeation of both atomic ions and small molecules between …

Vascular diseases, a leading cause of death in human, are strongly associated with
pathological damage to blood vessels. The selenoprotein (Sel) have been reported to play …

In myelinating Schwann cells, connection between myelin layers is mediated by gap
junction channels (GJCs) formed by docked connexin 32 (Cx32) hemichannels (HCs) …

Connexins (Cxs) function as gap junction (GJ) channels and hemichannels that mediate
intercellular and transmembrane signaling, respectively. Here, we investigated the proximal …

During developmental processes and wound healing, activation of living cells occurs with
spatiotemporal precision and leads to rapid release of soluble molecular signals, allowing …

Simple Summary Gap junction channels are composed of an assembly of connexin proteins
and allow direct communication between cells. They are highly conserved across …

Connexins allow intercellular communication by forming gap junction channels (GJCs)
between juxtaposed cells. Connexin26 (Cx26) can be regulated directly by CO 2. This is …

Erythrokeratodermia variabilis et progressiva (EKVP) is a rare hereditary skin disorder
characterized by hyperkeratotic plaques and erythematous patches that progressively …