Shiga toxins and stx phages: highly diverse entities

A Krüger, PMA Lucchesi - Microbiology, 2015 - microbiologyresearch.org
Shiga toxins are the main virulence factors of a group of Escherichia coli strains [Shiga toxin-
producing E. coli (STEC)] that cause severe human diseases, such as haemorrhagic colitis …

[HTML][HTML] Dual role of mechanisms involved in resistance to predation by protozoa and virulence to humans

S Sun, P Noorian, D McDougald - Frontiers in microbiology, 2018 - frontiersin.org
Most opportunistic pathogens transit in the environment between hosts and the environment
plays a significant role in the evolution of protective traits. The coincidental evolution …

Characterization of atypical Shiga toxin gene sequences and description of Stx2j, a new subtype

A Gill, F Dussault, T McMahon… - Journal of Clinical …, 2022 - Am Soc Microbiol
Shiga toxin (Stx) is the definitive virulence factor of Shiga toxin-producing Escherichia coli
(STEC). Stx variants are currently organized into a taxonomic system of three Stx1 (a, c, and …

Interactions of foodborne pathogens with free‐living protozoa: potential consequences for food safety

MJM Vaerewijck, J Baré, E Lambrecht… - … Reviews in Food …, 2014 - Wiley Online Library
Free‐living protozoa (FLP) are ubiquitous in natural ecosystems where they play an
important role in the reduction of bacterial biomass and the regeneration of nutrients …

The 2011 German Enterohemorrhagic Escherichia Coli O104:H4 Outbreak—The Danger Is Still Out There

S Kampmeier, M Berger, A Mellmann, H Karch… - Escherichia coli, a …, 2018 - Springer
Enterohemorrhagic Escherichia coli (EHEC) are Shiga toxin (Stx) producing bacteria
causing a disease characterized by bloody (or non-bloody) diarrhea, which might progress …

Oxidative Stress in Shiga Toxin Production by Enterohemorrhagic Escherichia coli

K Licznerska, B Nejman-Faleńczyk… - Oxidative medicine …, 2016 - Wiley Online Library
Virulence of enterohemorrhagic Escherichia coli (EHEC) strains depends on production of
Shiga toxins. These toxins are encoded in genomes of lambdoid bacteriophages (Shiga …

The T rojan H orse of the microbiological arms race: phage‐encoded toxins as a defence against eukaryotic predators

JW Arnold, GB Koudelka - Environmental microbiology, 2014 - Wiley Online Library
Phage‐encoded S higa toxin (S tx) acts as a bacterial defence against the eukaryotic
predator T etrahymena. To function as an effective bacterial anti‐predator defence, S tx must …

Evolution of STEC virulence: Insights from the antipredator activities of Shiga toxin producing E. coli

GB Koudelka, JW Arnold, D Chakraborty - International Journal of Medical …, 2018 - Elsevier
Shiga toxin-producing Escherichia coli (STEC) are a diverse group of strains that are
implicated in over 270,000 cases of human illness annually in the United States alone …

[HTML][HTML] Valid presumption of Shiga toxin-mediated damage of developing erythrocytes in EHEC-associated hemolytic uremic syndrome

J Detzner, G Pohlentz, J Müthing - Toxins, 2020 - mdpi.com
The global emergence of clinical diseases caused by enterohemorrhagic Escherichia coli
(EHEC) is an issue of great concern. EHEC release Shiga toxins (Stxs) as their key virulence …

[HTML][HTML] Protozoan Predation of Escherichia coli O157:H7 Is Unaffected by the Carriage of Shiga Toxin-Encoding Bacteriophages

CE Schmidt, S Shringi, TE Besser - PloS one, 2016 - journals.plos.org
Escherichia coli O157: H7 is a food-borne bacterium that causes hemorrhagic diarrhea and
hemolytic uremic syndrome in humans. While cattle are a known source of E. coli O157: H7 …