Background Jaw-bone defects caused by various diseases lead to aesthetic and functional
complications, which can seriously affect the life quality of patients. Current treatments …

The favorable microstructure and bioactivity of tissue-engineered bone scaffolds are closely
associated with the regenerative efficacy of bone defects. For the treatment of large bone …

Bone damage may be triggered by a variety of factors, and the damaged area often requires
a bone graft. Bone tissue engineering can serve as an alternative strategy for repairing large …

Microchannel networks within engineered 3D scaffold can allow nutrient exchange and
rapid blood vessels formation. However, fabrication of a bone microenvironment‐mimicking …

Bioprinting has seen significant progress in recent years for the fabrication of bionic tissues
with high complexity. However, it remains challenging to develop cell‐laden bioinks …

Diabetes has been associated with postoperative complications, such as increased risk of
tissue infection and impaired tissue repair caused by destabilization of hypoxia-inducible …

The repair of diabetic bone defects is still challenging as the innate healing process is
impaired by adverse microenvironments such as excessive reactive oxygen species (ROS) …

Vascularization and bone regeneration are closely related in the process of bone
remodeling, and designing a bioactive scaffold with pro-angiogenic and osteogenic …

In the process of bone tissue regeneration, regulation of osteogenesis–angiogenesis
coupling is of great importance. Therefore, dimethyloxallyl glycine (DMOG) is loaded by …

Prolyl hydroxylases (PHD) inhibitors have been observed to improve drug distribution in
mice tumors via blood vessel normalization, increasing the effectiveness of chemotherapy …