Chronic pain affects a large part of the population causing functional disability, being often
associated with coexisting psychological disorders, such as depression and anxiety …

Nutrition plays an important role in pain management. Healthy eating patterns are
associated with reduced systemic inflammation, as well as lower risk and severity of chronic …

Spinal cord stimulation is a proven effective therapy for treating chronic neuropathic pain.
Previous work in our laboratory demonstrated that spinal cord stimulation based on a …

Chronic pain is an unpleasant sensory and emotional experience that persists or recurs
more than three months and may extend beyond the expected time of healing. Recently …

Chronic pain is known to be caused by sensitization within the pain circuits. An imbalance
occurs between excitatory and inhibitory transmission that enables this sensitization to form …

Inflammatory pain is the perception of noxious stimuli that occurs during inflammation or an
immune response. Glial cells are widespread in the central and peripheral nervous systems …

Neuropathic pain, a disease of the somatosensory nervous system, afflicts many individuals
and adequate management with current pharmacotherapies remains elusive. The …

Previously, we have reported that ginsenoside Rg3 has typical activities for neuroprotection
and Aβ42 clearance by modulating microglia. In this study, we determined the pivotal role of …

Current evidence suggests that activation of glial and immune cells leads to increased
production of proinflammatory mediators, creating a neuroinflammatory state …

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is one of the most common
diseases of the male urological system while the etiology and treatment of CP/CPPS remain …