Accelerated MR spectroscopic imaging—a review of current and emerging techniques
Over more than 30 years in vivo MR spectroscopic imaging (MRSI) has undergone an
enormous evolution from theoretical concepts in the early 1980s to the robust imaging …
enormous evolution from theoretical concepts in the early 1980s to the robust imaging …
Hyperpolarized 13C MRI: A novel approach for probing cerebral metabolism in health and neurological disease
Cerebral metabolism is tightly regulated and fundamental for healthy neurological function.
There is increasing evidence that alterations in this metabolism may be a precursor and …
There is increasing evidence that alterations in this metabolism may be a precursor and …
The use of hyperpolarised 13C-MRI in clinical body imaging to probe cancer metabolism
R Woitek, FA Gallagher - British journal of cancer, 2021 - nature.com
Metabolic reprogramming is one of the hallmarks of cancer and includes the Warburg effect,
which is exhibited by many tumours. This can be exploited by positron emission tomography …
which is exhibited by many tumours. This can be exploited by positron emission tomography …
Emerging technologies to image tissue metabolism
Due to the implication of altered metabolism in a large spectrum of tissue function and
disease, assessment of metabolic processes becomes essential in managing health. In this …
disease, assessment of metabolic processes becomes essential in managing health. In this …
Parallel nuclear magnetic resonance spectroscopy
Nuclear magnetic resonance (NMR) spectroscopy is a principal analytical technique used
for the structure elucidation of molecules. This Primer covers different approaches to …
for the structure elucidation of molecules. This Primer covers different approaches to …
Dissolution DNP for in vivo preclinical studies
A Comment - Journal of Magnetic Resonance, 2016 - Elsevier
The tremendous polarization enhancement afforded by dissolution dynamic nuclear
polarization (DNP) can be taken advantage of to perform preclinical in vivo molecular and …
polarization (DNP) can be taken advantage of to perform preclinical in vivo molecular and …
Coil combination methods for multi-channel hyperpolarized 13C imaging data from human studies
Effective coil combination methods for human hyperpolarized 13 C spectroscopy multi-
channel data had been relatively unexplored. This study implemented and tested several …
channel data had been relatively unexplored. This study implemented and tested several …
Studies of metabolism using 13C MRS of hyperpolarized probes
MM Chaumeil, C Najac, SM Ronen - Methods in enzymology, 2015 - Elsevier
First described in 2003, the dissolution dynamic nuclear polarization (DNP) technique,
combined with 13 C magnetic resonance spectroscopy (MRS), has since been used in …
combined with 13 C magnetic resonance spectroscopy (MRS), has since been used in …
Hyperpolarized carbon-13 magnetic resonance spectroscopic imaging: a clinical tool for studying tumour metabolism
Glucose metabolism in tumours is reprogrammed away from oxidative metabolism, even in
the presence of oxygen. Non-invasive imaging techniques can probe these alterations in …
the presence of oxygen. Non-invasive imaging techniques can probe these alterations in …
Fast imaging for hyperpolarized MR metabolic imaging
MRI with hyperpolarized carbon‐13 agents has created a new type of noninvasive, in vivo
metabolic imaging that can be applied in cell, animal, and human studies. The use of 13C …
metabolic imaging that can be applied in cell, animal, and human studies. The use of 13C …