Intercellular mitochondrial transfer as a means of tissue revitalization

D Liu, Y Gao, J Liu, Y Huang, J Yin, Y Feng… - Signal transduction and …, 2021 - nature.com
As the crucial powerhouse for cell metabolism and tissue survival, the mitochondrion
frequently undergoes morphological or positional changes when responding to various …

Mechanisms of mesenchymal stem/stromal cell function

JL Spees, RH Lee, CA Gregory - Stem cell research & therapy, 2016 - Springer
The past decade has seen an explosion of research directed toward better understanding of
the mechanisms of mesenchymal stem/stromal cell (MSC) function during rescue and repair …

Intercellular nanotubes mediate mitochondrial trafficking between cancer and immune cells

T Saha, C Dash, R Jayabalan, S Khiste… - Nature …, 2022 - nature.com
Cancer progresses by evading the immune system. Elucidating diverse immune evasion
strategies is a critical step in the search for next-generation immunotherapies for cancer …

[HTML][HTML] Mitochondria on the move: Horizontal mitochondrial transfer in disease and health

LF Dong, J Rohlena, R Zobalova, Z Nahacka… - Journal of Cell …, 2023 - rupress.org
Mammalian genes were long thought to be constrained within somatic cells in most cell
types. This concept was challenged recently when cellular organelles including …

Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy

T Ahmad, S Mukherjee, B Pattnaik, M Kumar… - The EMBO …, 2014 - embopress.org
There is emerging evidence that stem cells can rejuvenate damaged cells by mitochondrial
transfer. Earlier studies show that epithelial mitochondrial dysfunction is critical in asthma …

Trophic effects of mesenchymal stem cells in tissue regeneration

Y Fu, L Karbaat, L Wu, J Leijten, SK Both… - … Engineering Part B …, 2017 - liebertpub.com
Mesenchymal stem cells (MSCs) are considered to hold great therapeutic value for cell-
based therapy and for tissue regeneration in particular. Recent evidence indicates that the …

[HTML][HTML] Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium

NA Mabbott, DS Donaldson, H Ohno, IR Williams… - Mucosal …, 2013 - Elsevier
The transcytosis of antigens across the gut epithelium by microfold cells (M cells) is
important for the induction of efficient immune responses to some mucosal antigens in …

Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies

M Tardivel, S Bégard, L Bousset, S Dujardin… - Acta neuropathologica …, 2016 - Springer
A given cell makes exchanges with its neighbors through a variety of means ranging from
diffusible factors to vesicles. Cells use also tunneling nanotubes (TNTs), filamentous-actin …

Mitochondrial transfer in cancer: a comprehensive review

LX Zampieri, C Silva-Almeida, JD Rondeau… - International journal of …, 2021 - mdpi.com
Depending on their tissue of origin, genetic and epigenetic marks and microenvironmental
influences, cancer cells cover a broad range of metabolic activities that fluctuate over time …

Mesenchymal stem cells rescue injured endothelial cells in an in vitro ischemia–reperfusion model via tunneling nanotube like structure-mediated mitochondrial …

K Liu, K Ji, L Guo, W Wu, H Lu, P Shan, C Yan - Microvascular research, 2014 - Elsevier
Mesenchymal stem cells can be used as a novel treatment of ischemic vascular disease;
however, their therapeutic effect and mechanism of action require further evaluation …