Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

Endocrine-disrupting chemicals (EDCs) have significant impacts on biological systems, and
have been shown to interfere with physiological systems, especially by disrupting the …

The obesity epidemic shows no signs of abatement. Genetics and overnutrition together with
a dramatic decline in physical activity are the alleged main causes for this pandemic. While …

Aging is a progressive and irreversible pathophysiological process that manifests as the
decline in tissue and cellular functions, along with a significant increase in the risk of various …

Abstract Background Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor,
has been extensively demonstrated to be associated with metabolic disorders, including …

Metabolomics and exposomics are important in the studies of human health and diseases.
Chemical isotope labeling (CIL) combined with mass spectrometry (MS) can not only …

There is growing concern regarding the health and safety issues of endocrine-disrupting
chemicals (EDCs). Long-term exposure to EDCs has alarming adverse health effects …

Nonalcoholic fatty liver disease (NAFLD) has emerged as the predominant cause of chronic
liver injury; however, the mechanisms underlying its progression have not been fully …

This study aimed to investigate insomnia-related alterations in gut microbiota and their
association with serum metabolites. A total of 24 patients with insomnia disorder and 22 …

Perfluorohexyl sulfonate (PFHxS) is the third most abundant per-and polyfluoroalkyl
substances and its developmental toxicity remains very poorly understood. Here, pregnant …