[HTML][HTML] Synthesis, in vitro analysis and molecular docking study of novel benzoxazole-based oxazole derivatives for the treatment of Alzheimer's disease

R Hussain, F Rahim, W Rehman, S Khan… - Arabian Journal of …, 2023 - Elsevier
Alzheimer's disease (AD) is treated by targeting cholinesterase enzymes like
acetylcholinesterase and butyrylcholinesterase, and these enzymes' inhibitors serve as …

Catalyst Design and Feature Engineering to Improve Selectivity and Reactivity in Two Simultaneous Cross-Coupling Reactions

K Motojima, A Sen, YMA Yamada… - Journal of Chemical …, 2023 - ACS Publications
Highly active catalysts are required in numerous industrial fields; therefore, to minimize costs
and development time, catalyst design using machine learning has attracted significant …

Resveratrol–maltol and resveratrol–thiophene hybrids as cholinesterase inhibitors and antioxidants: synthesis, biometal chelating capability and crystal structure

M Mlakić, L Fodor, I Odak, O Horváth, MJ Lovrić… - Molecules, 2022 - mdpi.com
New resveratrol–thiophene and resveratrol–maltol hybrids were synthesized as
cholinesterase inhibitors and antioxidants. As with photostability experiments, biological …

Design, Synthesis, In Vitro Biological Evaluation and In Silico Molecular Docking Study of Benzimidazole-Based Oxazole Analogues: A Promising …

R Hussain, F Rahim, H Ullah, S Khan, M Sarfraz… - Molecules, 2023 - mdpi.com
Alzheimer's disease (AD) is a degenerative neurological condition that severely affects the
elderly and is clinically recognised by a decrease in cognition and memory. The treatment of …

Synthesis, photochemistry and computational study of novel 1, 2, 3-triazole heterostilbenes: Expressed biological activity of their electrocyclization photoproducts

M Mlakić, I Faraho, I Odak, S Talić, A Vukovinski… - Bioorganic …, 2022 - Elsevier
Abstract New 1, 2, 3-triazolostilbenes were synthesized and photochemically transformed to
substituted naphthotriazoles as electrocyclization products in high isolated yields for …

Synthesis, photochemistry, computational study and potential application of new styryl-thiophene and naphtho-thiophene benzylamines

M Mlakić, I Odak, I Faraho, M Bosnar… - International journal of …, 2022 - mdpi.com
In this research, the synthesis, photochemistry, and computational study of new cis-and trans-
isomers of amino-thienostilbenes is performed to test the efficiency of their production and …

[HTML][HTML] Cholinesterase Inhibition and Antioxidative Capacity of New Heteroaromatic Resveratrol Analogs: Synthesis and Physico—Chemical Properties

M Mlakić, S Talić, I Odak, D Barić, I Šagud… - International journal of …, 2024 - ncbi.nlm.nih.gov
The targeted compounds in this research, resveratrol analogs 1–14, were synthesized as
mixtures of isomers by the Wittig reaction using heterocyclic triphenylphosphonium salts and …

Benzobicyclo [3.2. 1] octene derivatives as a new class of cholinesterase inhibitors

T Čadež, A Grgičević, R Ahmetović, D Barić, NM Hrvat… - Molecules, 2020 - mdpi.com
A library of amine, oxime, ether, epoxy and acyl derivatives of the benzobicyclo [3.2. 1]
octene were synthesized and evaluated as inhibitors of both human acetylcholinesterase …

Natural deep eutectic solvents improve the solubility of acetylcholinesterase reactivator RS194B

M Panić, NM Hrvat, M Štokić, IR Redovniković… - … chemistry and pharmacy, 2022 - Elsevier
Natural deep eutectic solvents (NADES) were studied as alternative solvents for the
preparation of oxime RS194B, which is considered as a potent antidote for …

[PDF][PDF] Effect of nanocapsules and extract of Metarhizium anisopliae in inhibiting acetylcholine esterase enzyme in Musca domestica larvae.

AAA Hammed, HI Al Shammari, SA Kathiar - Baghdad Science Journal, 2024 - iasj.net
M. domestica is the most important insect that transmit pathogens for diseases in the world.
The use of nanotechnology is eco-friendly method in control pests. The study aims to …