[HTML][HTML] Reciprocal regulation of mesenchymal stem cells and immune responses
Mesenchymal stem/stromal cells (MSCs) exist in almost all tissues and participate in tissue
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …
regeneration and homeostasis. In-vitro-expanded MSCs are employed as therapeutics for …
[HTML][HTML] Mesenchymal stromal cells: putative microenvironmental modulators become cell therapy
M Krampera, K Le Blanc - Cell stem cell, 2021 - cell.com
An exceptional safety profile has been shown in a large number of cell therapy clinical trials
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …
Trends in mesenchymal stem cell clinical trials 2004-2018: Is efficacy optimal in a narrow dose range?
M Kabat, I Bobkov, S Kumar… - Stem cells translational …, 2020 - academic.oup.com
The number of clinical trials using mesenchymal stem cells (MSCs) has increased since
2008, but this trend slowed in the past several years and dropped precipitously in 2018 …
2008, but this trend slowed in the past several years and dropped precipitously in 2018 …
Immunomodulation by therapeutic mesenchymal stromal cells (MSC) is triggered through phagocytosis of MSC by monocytic cells
SFH de Witte, F Luk, JM Sierra Parraga, M Gargesha… - stem cells, 2018 - academic.oup.com
Mesenchymal stem or stromal cells (MSC) are under investigation as a potential
immunotherapy. MSC are usually administered via intravenous infusion, after which they are …
immunotherapy. MSC are usually administered via intravenous infusion, after which they are …
Pathogenesis and treatment of Sjogren's syndrome: review and update
Q Zhan, J Zhang, Y Lin, W Chen, X Fan… - Frontiers in …, 2023 - frontiersin.org
Sjogren's syndrome (SS) is a chronic autoimmune disease accompanied by multiple
lesions. The main manifestations include dryness of the mouth and eyes, along with …
lesions. The main manifestations include dryness of the mouth and eyes, along with …
Salivary gland function, development, and regeneration
Salivary glands produce and secrete saliva, which is essential for maintaining oral health
and overall health. Understanding both the unique structure and physiological function of …
and overall health. Understanding both the unique structure and physiological function of …
[HTML][HTML] Current state of stem cell-based therapies: an overview
RM Aly - Stem cell investigation, 2020 - ncbi.nlm.nih.gov
Recent research reporting successful translation of stem cell therapies to patients have
enriched the hope that such regenerative strategies may one day become a treatment for a …
enriched the hope that such regenerative strategies may one day become a treatment for a …
Mesenchymal stem/stromal cells for rheumatoid arthritis treatment: an update on clinical applications
M Lopez-Santalla, R Fernandez-Perez, MI Garin - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects the lining of
the synovial joints leading to stiffness, pain, inflammation, loss of mobility, and erosion of …
the synovial joints leading to stiffness, pain, inflammation, loss of mobility, and erosion of …
Advances in mesenchymal stem cell therapy for immune and inflammatory diseases: Use of cell-free products and human pluripotent stem cell-derived mesenchymal …
LT Wang, KJ Liu, HK Sytwu, ML Yen… - Stem cells translational …, 2021 - academic.oup.com
Mesenchymal stem cell therapy (MSCT) for immune and inflammatory diseases continues to
be popular based on progressive accumulation of preclinical mechanistic evidence. This …
be popular based on progressive accumulation of preclinical mechanistic evidence. This …
Stem cell therapies for wound healing
N Kosaric, H Kiwanuka, GC Gurtner - Expert opinion on biological …, 2019 - Taylor & Francis
Introduction: Aberrant wound healing is a significant healthcare problem, posing a
substantial burden on patients, their families, and the healthcare system. Existing treatment …
substantial burden on patients, their families, and the healthcare system. Existing treatment …