This review addresses the oncopharmacological properties of curcumin at the molecular
level. First, the interactions between curcumin and its molecular targets are addressed on …

There are more than half a million incident cases of squamous-cell carcinoma of the head
and neck worldwide each year, primarily affecting the oropharynx, oral cavity, hypopharynx …

Background The epidermal growth factor receptor (EGFR), which participates in signaling
pathways that are deregulated in cancer cells, commonly appears on colorectal-cancer …

Aberrant epidermal growth factor receptor (EGFR) signaling is common in cancer. Increased
expression of wild type and mutant EGFR is a widespread feature of diverse types of cancer …

The management of cancer involves procedures, which include surgery, radiotherapy and
chemotherapy. Development of chemoresistance is a persistent problem during the …

Radiation is a significant treatment for patients with head and neck cancer. Despite
advances to improve treatment, many tumors acquire radiation resistance resulting in poor …

We examined effects of the anti-epidermal growth factor receptor monoclonal antibody C225
on proliferation, cell cycle phase distribution, apoptosis, and radiosensitivity in squamous …

Apoptosis is a finely regulated process that serves to determine the fate of cells in response
to various stresses. One such stress is DNA damage, which not only can signal repair …

During the past 20 years, the advent of neoadjuvant, primary, and adjuvant concurrent
chemoradiotherapy has improved cancer care dramatically. Significant contributions have …

Ionizing radiation, but not stimulation with epidermal growth factor (EGF), triggers EGF
receptor (EGFR) import into the nucleus in a probably karyopherin α-linked manner. An …