Synthesis of a new sulfadimidine Schiff base and their nano complexes as potential anti-COVID-19 and anti-cancer activity

S Hosny, MS Ragab, RF Abd El-Baki - Scientific Reports, 2023 - nature.com
The primary objective of this study was to describe the cytotoxicity on HEPG-2 cells and to
study the COVID‑19 activities of the novel H2L ligand and its Cr and Cu nano-complexes. As …

Multidimensional in silico strategy for identification of natural polyphenols-based SARS-CoV-2 main protease (Mpro) inhibitors to unveil a hope against COVID-19

Ş Adem, V Eyupoglu, IM Ibrahim, I Sarfraz… - Computers in biology …, 2022 - Elsevier
Abstract SARS-CoV-2, a rapidly spreading new strain of human coronavirus, has affected
almost all the countries around the world. The lack of specific drugs against SARS-CoV-2 is …

Synthesis, structural characterization, and antimicrobial evaluation of new mononuclear mixed ligand complexes based on furfural-type imine ligand, and 2, 2 …

BA Ismail, ZH Abd El-Wahab, OAM Ali, DA Nassar - Scientific Reports, 2023 - nature.com
The present investigation goal was to investigate the chemistry of four new mononuclear
mixed ligand Fe (III), Co (II), Cu (II), and Cd (II) complexes constructed from furfural-type …

[HTML][HTML] Designing of novel nano-sized coordination compounds based on Spinacia oleracea extract: Synthesis, structural characterization, molecular docking …

S Hosny, MR Shehata, SA Aly, AH Alsehli… - Inorganic Chemistry …, 2024 - Elsevier
A novel series of nano-sized metal chelates of 1-((E)-(2-mercaptophenylimino) methyl)
naphthalen-2-ol (H 2 L) Azo-methine ligand with Fe (III), Ni (II) and Ag (II) were prepared and …

Designing, Characterization, DFT, Biological Effectiveness, and Molecular Docking Analysis of Novel Fe(III), Co(II), and Cu(II) Complexes Based on 4-Hydroxy-2H-pyrano[3,2-c] …

MM Khalaf, HM Abd El-Lateef, M Gouda… - ACS …, 2024 - ACS Publications
The main target of the current framework is the designing and synthesizing of novel iron (III),
cobalt (II), and cupper (II) complex compounds emanating from bioactive nucleus, 4-hydroxy …

Practical and computational studies on novel Schiff base complexes derived from green synthesis approach: conductometry as well as in-vitro screening supported by …

R Shah, H Katouah, AA Sedayo, M Abualnaja… - Journal of Molecular …, 2020 - Elsevier
A new Schiff base ligand was prepared and characterized then used to synthesize new
metal ion complexes using ball milling technique. These complexes were elucidated by …

Synthesis, characterization, and multifunctional applications of novel metal complexes based on thiazolylazo dye

MN El‐Nahass, EA Bakr, MM El‐Gamil… - Applied …, 2022 - Wiley Online Library
Herein, a novel ligand, namely, N, N‐dimethyl‐4‐((4‐(pyridin‐2‐yl) thiazol‐2‐yl) diazenyl)
aniline, and its solid Mn (II), Co (II), Ni (II), and Cu (II) complexes have been synthesized and …

New nanometric metal complexes based on thiazole derivative as potential antitumor and antimicrobial agents: Full structural elucidation, docking simulation and …

AM Khedr, HSA Mandour, KM Wahdan… - Journal of Molecular …, 2024 - Elsevier
Abstract Novel Mn (II), Ni (II), Zr (IV) and Cd (II) nanosized complexes of thiazole Schiff base
derivative (HL) were synthesized for further medicinal applications. The inspected …

Facile synthesis and deliberate characterization for new hydrazide complexes; cyclic voltammetry, crystal packing, eukaryotic DNA degradation and in-silico studies

H Katouah, A Sayqal, AM Al-Solimy… - Journal of Molecular …, 2020 - Elsevier
New metal ion complexes were synthesized from new NO donor hydrazide ligand derived
from acid hydrazide. All new synthesizes were investigated by all available analytical …

Elucidation for coordination features of hydrazide ligand under influence of variable anions in bivalent transition metal salts; green synthesis, biological activity …

K Alkhamis, F Alkhatib, A Alsoliemy, AF Alrefaei… - Journal of Molecular …, 2021 - Elsevier
Synthesis of new N′-cyclohexylidene-3‑hydroxy-2-naphthohydrazide (H 2 L) complexes
was carried out by ball milling technique in the lack of solvent (green approach) and then …