Air pollution-induced placental alterations: an interplay of oxidative stress, epigenetics, and the aging phenotype?

ND Saenen, DS Martens, KY Neven, R Alfano… - Clinical …, 2019 - Springer
Abstract According to the “Developmental Origins of Health and Disease”(DOHaD) concept,
the early-life environment is a critical period for fetal programming. Given the …

[HTML][HTML] Exposure to ambient air pollution in the first 1000 days of life and alterations in the DNA methylome and telomere length in children: a systematic review

E Isaevska, C Moccia, F Asta, F Cibella… - Environmental …, 2021 - Elsevier
Background Exposure to air pollution during the first 1000 days of life (from conception to the
2 nd year of life) might be of particular relevance for long-term child health. Changes in …

Prenatal particulate air pollution and DNA methylation in newborns: an epigenome-wide meta-analysis

O Gruzieva, CJ Xu, P Yousefi, C Relton… - Environmental …, 2019 - ehp.niehs.nih.gov
Background: Prenatal exposure to air pollution has been associated with childhood
respiratory disease and other adverse outcomes. Epigenetics is a suggested link between …

Air pollution and children's health—a review of adverse effects associated with prenatal exposure from fine to ultrafine particulate matter

NM Johnson, AR Hoffmann, JC Behlen, C Lau… - … health and preventive …, 2021 - Springer
Background Particulate matter (PM), a major component of ambient air pollution, accounts
for a substantial burden of diseases and fatality worldwide. Maternal exposure to PM during …

Air pollution associated epigenetic modifications: Transgenerational inheritance and underlying molecular mechanisms

A Shukla, N Bunkar, R Kumar, A Bhargava… - Science of The Total …, 2019 - Elsevier
Air pollution is one of the leading causes of deaths in Southeast Asian countries including
India. Exposure to air pollutants affects vital cellular mechanisms and is intimately linked …

Risk factors during first 1,000 days of life for carotid intima-media thickness in infants, children, and adolescents: A systematic review with meta-analyses

AM Epure, M Rios-Leyvraz, D Anker… - PLoS …, 2020 - journals.plos.org
Background The first 1,000 days of life, ie, from conception to age 2 years, could be a critical
period for cardiovascular health. Increased carotid intima-media thickness (CIMT) is a …

Linking prenatal environmental exposures to lifetime health with epigenome-wide association studies: state-of-the-science review and future recommendations

KM Bakulski, F Blostein, SJ London - Environmental health …, 2023 - ehp.niehs.nih.gov
Background: The prenatal environment influences lifetime health; epigenetic mechanisms
likely predominate. In 2016, the first international consortium paper on cigarette smoking …

Particulate matter-induced cardiovascular dysfunction: a mechanistic insight

NU Ain, SUR Qamar - Cardiovascular Toxicology, 2021 - Springer
Air pollution and particulate matter (PM) are significant factors for adverse health effects
most prominently cardiovascular disease (CVD). PM is produced from various sources …

Personal exposure to PM2. 5 constituents associated with gestational blood pressure and endothelial dysfunction

B Xia, Y Zhou, Q Zhu, Y Zhao, Y Wang, W Ge… - Environmental …, 2019 - Elsevier
Ambient fine particulate matter (PM 2.5) pollution has been implicated in the development of
hypertensive disorders of pregnancy. However, evidence on the effects of PM 2.5-derived …

The impact of air pollution on our epigenome: how far is the evidence?(a systematic review)

R Alfano, Z Herceg, TS Nawrot… - Current environmental …, 2018 - Springer
Abstract Purpose of Review This systematic review evaluated existing evidence linking air
pollution exposure in humans to major epigenetic mechanisms: DNA methylation …