Rare actinomycetes are highly valued as potential sources of novel bioactive secondary
metabolites. Among these rare actinomycetes, the genus Saccharothrix is particularly …

Nano-liposomes are the newly developed delivery systems for cancer therapy that are
finding a position particularly suitable as peptide and protein carriers. These are three …

A novel actinobacterium, strain HNM0039T, was isolated from a marine sponge sample
collected at the coast of Wenchang, Hainan, China and its polyphasic taxonomy was …

Microbial specialised metabolism is full of valuable natural products that are applied
clinically, agriculturally, and industrially. The genes that encode their biosynthesis are often …

Streptomyces sp. NTK 937, producer of benzoxazole antibiotic caboxamycin, produces in
addition a methyl ester derivative, O‐methylcaboxamycin. Caboxamycin cluster, comprising …

Two new cyclized thiolopyrrolone derivatives, namely, thiolopyrrolone A (1) and 2, 2-
dioxidothiolutin (2), together with the kn own compound, thiolutin (3) were identified from a …

Amide N-methylation is important for the activity and permeability of bioactive compounds
but can be challenging to perform selectively. The broad-spectrum antimicrobial natural …

A polyphasic approach was used to describe strain RB6PN25T, an actinobacterium isolated
from peat swamp forest soil in Rayong Province, Thailand. The strain was a Gram-stain …

StrR-like pathway-specific transcriptional regulators (PSRs) function as activators in the
biosynthesis of various antibiotics, including glycopeptides (GPAs), aminoglycosides …

Ilamycins are cyclopeptides with novel structures that have been isolated from different
Actinomycetes. They showed strong anti-tuberculosis activity and could serve as important …