Accumulating evidence indicates that ataxia-telangiectasia mutated kinase is critical for
maintaining cellular homeostasis and that it has both nuclear and cytoplasmic functions …

Polyglutamine diseases are characterized by selective dysfunction and degeneration of
specific types of neurons in the central nervous system. In addition, nonneuronal cells can …

Neurological disorders present a wide range of symptoms and challenges in diagnosis and
treatment. Cannabis sativa, with its diverse chemical composition, offers potential …

R-loops are DNA–RNA hybrids that play multifunctional roles in gene regulation, including
replication, transcription, transcription–replication collision, epigenetics, and preserving the …

Polyglutamine (polyQ) spinocerebellar ataxias (SCAs) comprise a group of autosomal
dominant neurodegenerative disorders caused by (CAG/CAA) n expansions. The elongated …

Polyglutamine (polyQ) disorders are a group of neurodegenerative diseases characterized
by the excessive expansion of CAG (cytosine, adenine, guanine) repeats within host …

Accumulating evidence indicates that ataxia-telangiectasia mutated kinase is critical for
maintaining cellular homeostasis and that it has both nuclear and cytoplasmic functions …

Most of the human genome is comprised of non-coding DNA. Satellite DNA (satDNA) is a
non-coding region, and it is one of the DNA types that contains repeated sequences …

This chapter focuses on the clinical application of mesenchymal stem cells (MSCs) for the
treatment of spinocerebellar ataxia (SCA). SCA is a progressive neurodegenerative disease …

Polyglutamine diseases are characterized by selective dysfunction and degeneration of
specific types of neurons in the central nervous system. In addition, nonneuronal cells can …